Evidence map›Paper›PMID 34401999›Full record

ArticleBrain topography2021

Unilateral Blinking: Insights from Stereo-EEG and Tractography.

Elisabeth Kaufmann, Joanna Bartkiewicz, Nicholas Fearns, Katharina Ernst, Christian Vollmar, Soheyl Noachtar

Open access · hybridAbstract read
In one paragraph

Article in Brain topography, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elisabeth KaufmannEpilepsy Center, Department of Neurology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany. elisabeth.kaufmann@med.uni-muenchen.de.ORCID 0000-0002-7582-2215
Joanna BartkiewiczEpilepsy Center, Department of Neurology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany.
Nicholas FearnsEpilepsy Center, Department of Neurology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany.
Katharina ErnstEpilepsy Center, Department of Neurology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany.
Christian Vollmar *Epilepsy Center, Department of Neurology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany.
Soheyl Noachtar *Epilepsy Center, Department of Neurology, University of Munich, Marchioninistr. 15, 81377, Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the neuroanatomical correlate of involuntary unilateral blinking in humans, using the example of patients with focal epilepsy. Patients with drug resistant focal epilepsy undergoing presurgical evaluation with stereotactically implanted EEG-electrodes (sEEG) were recruited from the local epilepsy monitoring unit. Only patients showing ictal unilateral blinking or unilateral blinking elicited by direct electrical stimulation were included (n = 16). MRI and CT data were used for visualization of the electrode positions. In two patients, probabilistic tractography with seeding from the respective electrodes was additionally performed. Three main findings were made: (1) involuntary unilateral blinking was associated with activation of the anterior temporal region, (2) tractography showed widespread projections to the ipsilateral frontal, pericentral, occipital, limbic and cerebellar regions and (3) blinking was observed predominantly in female patients with temporal lobe epilepsies. Unilateral blinking was found to be associated with an ipsilateral activation of the anterior temporal region. We suggest that the identified network is not part of the primary blinking control but might have modulating influence on ipsilateral blinking by integrating contextual information.

Indexed as

Drug Resistant EpilepsyEpilepsies, PartialEpilepsy, Temporal LobeBlinkingElectroencephalographyFemaleHumansDTIEpilepsyEye closureIntracranial EEG

Identifiers

PMID34401999
PMCPMC8384786
OpenAlexW3195612232

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.