Evidence map›Paper›PMID 34401962›Full record

ArticleNeurochemical research2021

Curcumin Alleviates Aβ

Min Liu, Xiaodan Zhang, Ying Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Min LiuDepartment of Basic Disciplines, Jiangxi Health Vocational College, Nanchang, 330052, China.
Xiaodan ZhangDepartment of Basic Disciplines, Jiangxi Health Vocational College, Nanchang, 330052, China.
Ying WangDepartment of Recuperation No.1, Dalian Rehabilitation and Recuperation Center, Dalian, 116016, China. yingwangvip123@163.com.
Jiangxi Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin has been reported to have a therapeutic effect on Alzheimer's disease (AD), but the specific mechanism remains to be elucidated. In the present research, we aimed to investigate the effect and molecular mechanism of curcumin on AD. Mouse primary hippocampal neuron cells were treated with various concentrations of beta-amyloid 42 (Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAnti-Inflammatory Agents, Non-SteroidalCognitionCurcuminMetabolic DiseasesMiceMice, TransgenicNeuronsPeptide FragmentsSirtuin 3Thyroid Hormone Receptors betaAmyloid beta-Peptidesamyloid beta-protein (1-42)Anti-Inflammatory Agents, Non-SteroidalCurcuminPeptide FragmentsSirt3 protein, mouseSirtuin 3Thyroid Hormone Receptors betaAlzheimer’s diseaseCurcuminThrb/SIRT3Transcriptional regulation

Identifiers

PMID34401962
OpenAlexW3194896455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.