ArticleCerebral cortex (New York, N.Y. : 1991)2022
Thalamocortical Mechanisms Regulating the Relationship between Transient Beta Events and Human Tactile Perception.
Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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Who cites it
32 citing papers in PubMed, 47 citations in OpenAlex.
- Transient frontal spectral events from EEG predict antidepressant response to sertraline in depression.Journal of psychiatric research · 2026Trial
- Uncovering putative neural mechanisms of neurotherapeutic impacts on EEG using the Human Neocortical Neurosolver.bioRxiv : the preprint server for biology · 2026Article
- Testing circuit-level theories of consciousness in humans.Trends in cognitive sciences · 2026Review
- Transient frontal spectral events from EEG predict antidepressant response to sertraline in depression.medRxiv : the preprint server for health sciences · 2026Article
- Article
- OPM-MEG reveals dynamics of beta bursts underlying attentional processes in sensory cortex.Scientific reports · 2025Article
- High-power transient 12-30 Hz beta event features as early biomarkers of Alzheimer's disease conversion: An MEG study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Transcallosal generation of phase-aligned beta bursts underlies TMS-induced interhemispheric inhibition.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Distinct functions for beta and alpha bursts in gating of human working memory.Nature communications · 2024Article
- Oscillations in an artificial neural network convert competing inputs into a temporal code.PLoS computational biology · 2024Article
- Frontoparietal beta event characteristics are associated with early life stress and psychiatric symptoms in adults.Brain and cognition · 2024Article
- Biophysical Modeling of Frontocentral ERP Generation Links Circuit-Level Mechanisms of Action-Stopping to a Behavioral Race Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neuronal Modeling of Cross-Sensory Visual Evoked Magnetoencephalography Responses in the Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neuronal modeling of magnetoencephalography responses in auditory cortex to auditory and visual stimuli.bioRxiv : the preprint server for biology · 2024Article
- Methods and considerations for estimating parameters in biophysically detailed neural models with simulation based inference.PLoS computational biology · 2024Article
- Human Sensorimotor Beta Event Characteristics and Aperiodic Signal Are Highly Heritable.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Distinct neocortical mechanisms underlie human SI responses to median nerve and laser-evoked peripheral activation.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Bursting with Potential: How Sensorimotor Beta Bursts Develop from Infancy to Adulthood.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Pre-treatment frontal beta events are associated with executive dysfunction improvement after repetitive transcranial magnetic stimulation for depression: A preliminary report.Journal of psychiatric research · 2023Article
- Cortical origin of theta error signals.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Transient neocortical events with high spectral power in the 15-29 Hz beta band are among the most reliable predictors of sensory perception. Prestimulus beta event rates in primary somatosensory cortex correlate with sensory suppression, most effectively 100-300 ms before stimulus onset. However, the neural mechanisms underlying this perceptual association are unknown. We combined human magnetoencephalography (MEG) measurements with biophysical neural modeling to test potential cellular and circuit mechanisms that underlie observed correlations between prestimulus beta events and tactile detection. Extending prior studies, we found that simulated bursts from higher-order, nonlemniscal thalamus were sufficient to drive beta event generation and to recruit slow supragranular inhibition acting on a 300 ms timescale to suppress sensory information. Further analysis showed that the same beta-generating mechanism can lead to facilitated perception for a brief period when beta events occur simultaneously with tactile stimulation before inhibition is recruited. These findings were supported by close agreement between model-derived predictions and empirical MEG data. The postevent suppressive mechanism explains an array of studies that associate beta with decreased processing, whereas the during-event facilitatory mechanism may demand a reinterpretation of the role of beta events in the context of coincident timing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.