Evidence map›Paper›PMID 34401838›Full record

ArticleJTCVS techniques2021

Intraoperative fluorescence with indocyanine green in congenital cardiac surgery: Potential applications of a novel technology.

Sameh M Said, Gamal Marey, Gurumurthy Hiremath

Registry-linked trialAbstract read
In one paragraph

Article in JTCVS techniques, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07361523 (Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07361523 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery

Typeobservational_patient_registrySponsorBoston Children's HospitalRan2026 to 2027Enrolled50ConditionsCongenital Heart DiseaseArmsTissue oximeter (IntraOx)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Right atrial myxoma excision with pulmonary thrombectomy.Indian journal of thoracic and cardiovascular surgery · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sameh M SaidDivision of Pediatric Cardiovascular Surgery, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minn.
Gamal MareyDivision of Pediatric Cardiovascular Surgery, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minn.
Gurumurthy HiremathDivision of Pediatric Cardiology, Masonic Children's Hospital, University of Minnesota, Minneapolis, Minn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAchieving successful repair of congenital heart defects requires attention to detail. Careful evaluation of anastomotic site patency, reimplanted coronary arteries, location of epicardial coronaries, and myocardial perfusion may be necessary to ensure safe conduct of the operation and achieve excellent outcomes.

methodsIntraoperative fluorescence angiography (IOFA) was performed using indocyanine green in patients undergoing the following procedures: coronary artery reimplantation, coronary artery unroofing, evaluation of intraoperative coronary anatomy, reoperation requiring ventriculotomy, coarctation/interrupted aortic arch repair, systemic-to-pulmonary artery shunt, Norwood procedure, thoracic duct localization, and vascular rings.

resultsThe technique was feasible in all patients. No mortality or adverse events related to the dye were encountered. Adequate intraoperative imaging was obtained in 15 patients (20 images), which correlated well with postoperative studies. The imaging quality was superior for assessing shunt patency, myocardial perfusion, and anastomotic patency and determining the location of epicardial coronary arteries but was less so for assessing branch pulmonary arteries.

conclusionsIOFA is a useful and safe technique that can provide a quick on-table assessment of a variety of congenital surgical procedures. This may help answer questions that can minimize postoperative interventions and help ensure a smooth perioperative course and excellent outcomes.

Indexed as

Cc-TGA, congenitally corrected transposition of the great arteriescongenital heart surgeryCT, computed tomographyECMO, extracorporeal membrane oxygenationfluorescenceICG, indocyanine greenimaging technologyindocyanine greenIOFA, intraoperative fluorescence angiographyIVS, intact ventricular septumLAD, left anterior descending coronary arteryMBTS, modified Blalock–Taussig shuntPA, pulmonary atresiaRCA, right coronary arteryRVDCC, right ventricular-dependent coronary circulationSPYPHI

Identifiers

PMID34401838
PMCPMC8350758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.