Evidence map›Paper›PMID 34401661›Full record

ReviewiScience2021

Enteric glia in homeostasis and disease: From fundamental biology to human pathology.

Harry J Rosenberg, Meenakshi Rao

Open access · goldAbstract readReview
In one paragraph

Review in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Fluorescence-Activated Cell Sorting of Primary Enteric Glia.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Methods to Isolate Enteric Glia from hPSC-Derived Enteric Ganglioids.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Harry J RosenbergDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
Meenakshi RaoDepartment of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Beth Israel Deaconess Medical Center · USBoston Children's Hospital · US

Funding

Enteric Glia, Sexual Dimorphism and GI MotilityK08DK110532 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RAO, MEENAKSHI · 2016 to 2021
$862k
Androgen Regulation of Colonic MotilityR03DK125636 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI RAO, MEENAKSHI · 2020 to 2021
$266k
NIDDK NIH HHS K08 DK110532NIDDK NIH HHS R03 DK125636
6 · The paper itself

Abstract

Glia, the non-neuronal cells of the nervous system, were long considered secondary cells only necessary for supporting the functions of their more important neuronal neighbors. Work by many groups over the past two decades has completely overturned this notion, revealing the myriad and vital functions of glia in nervous system development, plasticity, and health. The largest population of glia outside the brain is in the enteric nervous system, a division of the autonomic nervous system that constitutes a key node of the gut-brain axis. Here, we review the latest in the understanding of these enteric glia in mammals with a focus on their putative roles in human health and disease.

Indexed as

GastroenterologyMicrobiomeNeuroscience

Identifiers

PMID34401661
PMCPMC8348155
OpenAlexW3179793209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.