Evidence map›Paper›PMID 34401640›Full record

ArticleResearch and practice in thrombosis and haemostasis2021

A mixed-methods study to evaluate a patient-designed tool to reduce harm from cancer-associated thrombosis: The EMPOWER study.

Elin Baddeley, Anna Torrens-Burton, Alisha Newman, Annmarie Nelson, Nikki Pease, Rosie Nelson, Simon Noble

Open access · goldAbstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Patient's Awareness of Cancer-Associated Thrombosis: A Canadian Nationwide Survey.TH open : companion journal to thrombosis and haemostasis · 2025
    Article
  4. Article
  5. Article
  6. A systematic approach to venous thromboembolism prevention: a focus on UK experience.Research and practice in thrombosis and haemostasis · 2023
    Article
  7. Article
  8. Observational
  9. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022
    Article
  10. Série « Prévenir la thrombose »: Sensibiliser les professionnels de la santé à la thrombose liée au cancer.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022
    Article
  11. Article
  12. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2021
    Article
  13. The significance of VTE in cancer: Introduction of the 'Spot the CLOT' series.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elin BaddeleyMarie Curie Palliative Care Research Centre Cardiff University Cardiff UK.
Anna Torrens-BurtonMarie Curie Palliative Care Research Centre Cardiff University Cardiff UK.
Alisha NewmanMarie Curie Palliative Care Research Centre Cardiff University Cardiff UK.
Annmarie NelsonMarie Curie Palliative Care Research Centre Cardiff University Cardiff UK.
Nikki PeaseVelindre University NHS Trust Cardiff UK.
Rosie NelsonBristol University Bristol UK.
Simon NobleMarie Curie Palliative Care Research Centre Cardiff University Cardiff UK.
Marie Curie · GBCardiff University · GBUniversity of Bristol · GBVelindre NHS Trust · GB

Funding

Marie Curie MCCC-FCO-11-C
6 · The paper itself

Abstract

introductionVenous thromboembolism (VTE) is a common and serious complication of systemic anticancer therapies. Delays in presentation increase risk of death or long-term morbidity.

backgroundA patient charity developed an information video for patients receiving systemic anticancer therapy including what to do if they developed symptoms of VTE. This was introduced into clinical practice in a regional cancer center and its impact compared with a district general hospital where the video was not used.

methodsA mixed-methods approach was used, comprising clinical audit data, patient surveys, and key informant interviews. The time between development of VTE symptoms and seeking medical evaluation was routinely recorded on patients attending a regional cancer-associated thrombosis service with systemic anticancer therapy-provoked VTE. The video was then embedded into clinical practice at the regional cancer center for 3 months. The primary outcome was the difference in time to presentation with VTE symptoms, between patients attending the regional cancer center and the district general hospital (which acted as control). Other outcomes included impact on radiology resources, patient knowledge, and perspectives of chemotherapy nurses.

resultsAddition of the video was associated with a lower mean time to presentation from 8.9 to 2.9 days (0.33 hazard ratio; 95% confidence interval, 4.5-7.4;

conclusionThe video was associated with reduced delays in diagnosis of systemic anticancer therapy-associated VTE by 6 days, thereby reducing long-term complications.

Indexed as

cancer‐associated thrombosismixed methodspatient informationqualitativevenous thromboembolism

Identifiers

PMID34401640
PMCPMC8357625
OpenAlexW3193907642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.