Evidence map›Paper›PMID 34401617›Full record

ArticleJournal of vascular surgery cases and innovative techniques2021

Deep vein thrombosis in the setting of Klippel-Trenaunay syndrome and sirolimus treatment.

Susana Fortich, Charles Ritchie, Marwan E Shaikh, Beau Toskich, Candido E Rivera, Young Erben

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular surgery cases and innovative techniques, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Susana FortichDivision of Vascular and Endovascular Surgery, Mayo Clinic Florida, Jacksonville, Fla.
Charles RitchieDivision of Vascular and Interventional Radiology, Mayo Clinic Florida, Jacksonville, Fla.
Marwan E ShaikhDivision of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, Fla.
Beau ToskichDivision of Vascular and Interventional Radiology, Mayo Clinic Florida, Jacksonville, Fla.
Candido E RiveraDivision of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, Fla.
Young ErbenDivision of Vascular and Endovascular Surgery, Mayo Clinic Florida, Jacksonville, Fla.
Mayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Klippel-Trenaunay syndrome (KTS) is a congenital vascular disorder characterized by the triad of cutaneous capillary malformation, lymphatic and venous anomalies, and soft tissue and bone overgrowth. Sirolimus is a mechanistic target of rapamycin inhibitor used as an immunosuppressive drug. It has also been used to improve and treat vascular malformations that can predispose to intravascular coagulopathy. We have described the case of a patient with KTS receiving a therapeutic anticoagulation dose, for whom sirolimus was initiated, and who had presented with an extensive venous thromboembolism. Correlations between the use of sirolimus in patients with KTS are limited, and cautious use and monitoring could be necessary.

Indexed as

Deep venous thrombosisKlippel Trenaunay syndromeSirolimus

Identifiers

PMID34401617
PMCPMC8358289
OpenAlexW3184007654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.