Evidence map›Paper›PMID 34401361›Full record

ArticleToxicology reports2021

Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test.

R H Mennen, N Hallmark, M Pallardy, R Bars, H Tinwell, A H Piersma

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

R H MennenNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection (GZB), Antonie van Leeuwenhoeklaan 9, 3721 MA, Bilthoven, The Netherlands.
N HallmarkBayer AG Crop Science Division, Monheim, Germany.
M PallardyInflammation, Microbiome and Immunosurveillance, Université Paris-Saclay, Inserm, Châtenay-Malabry, France.
R BarsBayer Crop Science, Sophia-Antipolis, France.
H TinwellBayer Crop Science, Sophia-Antipolis, France.
A H PiersmaNational Institute for Public Health and the Environment (RIVM), Centre for Health Protection (GZB), Antonie van Leeuwenhoeklaan 9, 3721 MA, Bilthoven, The Netherlands.
Bayer (France) · FRBayer (Germany) · DEInserm · FRNational Institute for Public Health and the Environment · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiac embryonic stem cell test (ESTc) originally used the differentiation of beating cardiomyocytes for embryotoxicity screenings of compounds. However, the ESTc consists of a heterogeneous cell population, including neural crest (NC) cells, which are important contributors to heart development

Indexed as

Cardiac embryonic stem cell testDevelopmental toxicologyNeural crestOrganophosphates

Identifiers

PMID34401361
PMCPMC8355823
OpenAlexW3191409450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.