ArticlePhotoacoustics2021
A photoacoustic finder fully integrated with a solid-state dye laser and transparent ultrasound transducer.
Article in Photoacoustics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06412211 (Clinical Utility of Photoacoustic Finder in Sentinel Lymph Node Detection in Breast Cancer - Pilot Study), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Utility of Photoacoustic Finder in Sentinel Lymph Node Detection in Breast Cancer - Pilot Study
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Photoacoustic imaging for cutaneous melanoma assessment: a comprehensive review.Journal of biomedical optics · 2024Pooled it
- Activatable smart contrast agents for photoacoustic imaging.Smart molecules : open access · 2026Review
- Fabrication of optically transparent ultrasound transducers to integrate light and sound in multimodal biomedical systems.Nature protocols · 2026Review
- Photoacoustic imaging: An emerging tool for intraoperative margin assessment in breast-conserving surgery.Photoacoustics · 2026Review
- Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Nanoengineered Macrophages for in vivo Three-Dimensional Photoacoustic Imaging and Immunotherapy of Acute Lung Injury.International journal of nanomedicine · 2026Article
- A handheld photoacoustic microscopic probe integrating a transparent ultrasound transducer and a fiber scanner.Nature communications · 2025Article
- Rapid cancer diagnosis using deep learning-powered label-free subcellular-resolution photoacoustic histology.Science advances · 2025Article
- High-frequency (> 65 MHz) broadband transparent transducer with ultrathin gold electrode for dual-mode photoacoustic and laser-induced ultrasound microscopy.Photoacoustics · 2025Article
- A comprehensive review of high-performance photoacoustic microscopy systems.Photoacoustics · 2025Review
- A clinical feasibility study of a photoacoustic finder for sentinel lymph node biopsy in breast cancer patients: A prospective cross-sectional study.Photoacoustics · 2025Article
- All-fiber three-wavelength laser for functional photoacoustic microscopy.Photoacoustics · 2025Article
- Quantitative volumetric photoacoustic assessment of vasoconstriction by topical corticosteroid application in mice skin.Photoacoustics · 2024Article
- Review on Photoacoustic Monitoring after Drug Delivery: From Label-Free Biomarkers to Pharmacokinetics Agents.Pharmaceutics · 2024Review
- 3D Multiparametric Photoacoustic Computed Tomography of Primary and Metastatic Tumors in Living Mice.ACS nano · 2024Article
- An ultrasensitive and broadband transparent ultrasound transducer for ultrasound and photoacoustic imaging in-vivo.Nature communications · 2024Article
- Large-field-of-view optical-resolution optoacoustic microscopy using a stationary silicon-photonics acoustic detector.Journal of biomedical optics · 2024Article
- High speed innovations in photoacoustic microscopy.Npj imaging · 2024Review
- Theoretical and experimental study on the detection limit of the micro-ring resonator based ultrasound point detectors.Photoacoustics · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The standard-of-care for evaluating lymph node status in breast cancers and melanoma metastasis is sentinel lymph node (SLN) assessment performed with a handheld gamma probe and radioisotopes. However, this method inevitably exposes patients and physicians to radiation, and the special facilities required limit its accessibility. Here, we demonstrate a non-ionizing, cost-effective, handheld photoacoustic finder (PAF) fully integrated with a solid-state dye laser and transparent ultrasound transducer (TUT). The solid-state dye laser handpiece is coaxially aligned with the spherically focused TUT. The integrated finder readily detected photoacoustic signals from a tube filled with methylene blue (MB) beneath a 22 mm thick layer of chicken tissue. In live animals, we also photoacoustically detected both SLNs injected with MB and subcutaneously injected melanomas. We believe that our radiation-free and inexpensive PAF can play a vital role in SLN assessment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.