Evidence map›Paper›PMID 34401309›Full record

ArticleRespiratory medicine case reports2021

Fatal autoimmune pneumonitis requiring bilobectomy and omental flap repair in a patient with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Stephanie A Kubala, Huy M Do, Elise M N Ferré, David S Schrump, Kenneth N Olivier, Jeffrey G Walls, Michail S Lionakis, Les R Folio

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Lessons From Prospective Longitudinal Follow-up of a French APECED Cohort.The Journal of clinical endocrinology and metabolism · 2025
    Observational
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Stephanie A KubalaNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Huy M DoRadiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, USA.
Elise M N FerréNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
David S SchrumpCenter for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Kenneth N OlivierPulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Jeffrey G WallsPulmonary and Critical Care, Novant Health, Charlotte, NC, USA.
Michail S LionakisNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Les R FolioRadiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · USNational Cancer Institute · USNovant Health · US

Funding

Immunopathogenesis of Fungal InfectionsZIAAI001175 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LIONAKIS, MICHAIL · 2012 to 2025
$23.9M
6 · The paper itself

Abstract

We present a severe case of progressive autoimmune pneumonitis requiring surgical intervention in a patient with the monogenic syndrome, autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). APECED is caused by loss-of-function mutations in the autoimmune regulator (

Indexed as

AIREAPECEDAPS-1Autoimmune pneumonitisBronchiectasisBronchopleural fistulaImmunomodulationOmental flap repair

Identifiers

PMID34401309
PMCPMC8349050
OpenAlexW3182411342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.