Evidence map›Paper›PMID 34401262›Full record

ArticleRespiratory medicine case reports2021

Intimal sarcoma of the pulmonary artery treated with neoadjuvant radiation prior to pulmonary artery resection and reconstruction.

Alexander Allen, Steven C Smith, Raghavendra Pillappa, Sosipatros Boikos, Benjamin Medalion, John Grizzard, Anthony Cassano, Timothy Harris

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pulmonary artery intimal sarcoma: Case report of a patient managed with multimodality treatment and a comprehensive literature review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alexander AllenDepartment of Radiation Oncology, Virginia Commonwealth University School of Medicine, 401 College Street, Richmond, VA, 23298-0037, USA.
Steven C SmithDepartment of Pathology, Division of Anatomic Pathology, Virginia Commonwealth University School of Medicine, 1200 East Marshall Street, Gateway Building, 6th Floor, Room 205, Box 980662, Richmond, VA, 23298-0662, USA.
Raghavendra PillappaDepartment of Pathology, Division of Anatomic Pathology, Virginia Commonwealth University School of Medicine, 1200 East Marshall Street, Gateway Building, 6th Floor, Room 204, Box 980662, Richmond, VA, 23298-0662, USA.
Sosipatros BoikosDepartment of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University School of Medicine, 1201, East Marshall Street, 11th Floor, Suite 11-206, Box 980070, Richmond, VA, 23298-0230, USA.
Benjamin MedalionDepartment of Surgery, Division of Cardiothoracic Surgery, Virginia Commonwealth University School of Medicine, 1200 East Broad Street, 7th Floor, Box 980645, Richmond, VA, 23298-0068, USA.
John GrizzardDepartment of Radiology, Virginia Commonwealth University School of Medicine, 1200 East Broad Street, North Wing, Room 2-013, Box 980470, Richmond, VA, 23298-0470, USA.
Anthony CassanoDepartment of Surgery, Division of Cardiothoracic Surgery, Virginia Commonwealth University School of Medicine, 1200 East Broad Street, 7th Floor, Box 980645, Richmond, VA, 23298-0068, USA.
Timothy HarrisDepartment of Radiation Oncology, Virginia Commonwealth University School of Medicine, 401 College Street, Box 980058, Richmond, VA, 23298-0037, USA.
Virginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intimal sarcoma (IS) is a rare malignancy arising in the great vessels or heart, most commonly in the pulmonary artery, primarily treated with surgical intervention. We report a case of IS of the pulmonary artery diagnosed after an endarterectomy to remove a suspected pulmonary embolism. The tumor could not be entirely resected and showed interval growth at post-operative follow up. Neoadjuvant radiotherapy was then delivered to improve resectability. Imaging confirmed decreased tumor size, and a surgical resection with pulmonary artery reconstruction and right upper lobectomy was then successfully performed. Adjuvant gemcitabine and docetaxel was later initiated. Four months post-operatively, the patient is alive without disease recurrence. While prior reports in the literature document use of adjuvant chemotherapy and radiotherapy for treatment of IS of the pulmonary artery, no prior experience has documented utility of neoadjuvant radiotherapy for improvement of resectability. Our experience suggests that neoadjuvant radiation should be considered to improve resectability in cases of borderline resectable IS of the pulmonary artery.

Indexed as

EndarterectomyIntimal sarcomaNeoadjuvantPulmonary arteryRadiation

Identifiers

PMID34401262
PMCPMC8348529
OpenAlexW3159175371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.