ArticleObesity science & practice2021
Sex steroids and adiposity in a prospective observational cohort of youth.
Article in Obesity science & practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Body roundness index outperforms traditional obesity metrics in predicting cardiometabolic risk among children and adolescents: the EMSNGS study.Frontiers in nutrition · 2026Article
- Association between endogenous sex hormones and adiposity in youth across a weight status spectrum.Pediatric research · 2025Article
- The role of prenatal maternal sex steroid hormones in weight and adiposity at birth and growth trajectories during infancy.International journal of obesity (2005) · 2025Article
- A better performing algorithm for identification of implausible growth data from longitudinal pediatric medical records.Scientific reports · 2024Article
- The role of prenatal maternal sex steroid hormones in weight and adiposity at birth and growth trajectories during infancy.Research square · 2024Article
- Epigenetic age acceleration is associated with speed of pubertal growth but not age of pubertal onset.Scientific reports · 2024Article
- Sex steroids and adiposity in a prospective observational cohort of youth.Obesity science & practice · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveAdiposity, particularly visceral adipose tissue (VAT), predicts adverse cardiovascular risk factor profiles in children as well as adults. Although endogenous sex steroids likely influence VAT in adults, such an association has not been established in youth. The association between childhood and adolescent sex steroids with adiposity, specifically VAT, was examined before and after adjustment for other hormone changes.
methodsThese analyses examined longitudinal associations between sex steroids (testosterone, estradiol, dehydroepiandrosterone [DHEA]) and magnetic resonance imaging assessments of VAT in 418 children, 49% of whom were non-White, at approximately 10 years old at Visit 1 (V1) and 17 years old at Visit 2 (V2). Linear mixed effects models adjusted for maternal education, household income, child caloric intake, physical activity, fasting insulin and leptin, and hepatic fat fraction. Differences in associations by race and pubertal stage were also assessed.
resultsAt V1, mean body mass index (BMI) for boys was 19.1 (4.7) kg/m
conclusionsTestosterone levels predict VAT in boys and girls, and DHEA predicts VAT in girls, even after adjustment for other hormone changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.