ArticleScientific data2021
Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers.
Erratum issuedAbstract readDataset
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Article in Scientific data, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers.
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43citing papers in PubMed
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed.
- A lightweight method for regression-based normalization of the cross-sectional area for cervical spinal cord atrophy assessment.Medical & biological engineering & computing · 2026Article
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- Segmentation of spinal rootlets across MRI contrasts with RootletSeg.Scientific reports · 2026Article
- Generalizable spinal cord multiple sclerosis lesion segmentation across MRI contrasts, protocols, and centers.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- Utility of diffusion tensor imaging and tractography (DTI/DTT) in the surgical resection of intramedullary spinal cord tumors: A scoping review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Assessing the cervical canal area in multiple sclerosis with spinal cord sagittal 2D T2-weighted sequences.Magma (New York, N.Y.) · 2026Article
- Quantitative assessment of asymptomatic spinal cord compression using MRI: a multi-center study.GeroScience · 2025Article
- Magnetization transfer MRI (MT-MRI) detects white matter damage beyond the primary site of compression in degenerative cervical myelopathy using a novel semi-automated analysis.Computers in biology and medicine · 2025Article
- A novel open-source ultrasound dataset with deep learning benchmarks for spinal cord injury localization and anatomical segmentation.Scientific reports · 2025Article
- Semiautomated Pipeline Effectively Assesses Severity and Monitor Disease Progression in Compressed Spinal Cord of Degenerative Cervical Myelopathy Patients.Neurosurgery practice · 2025Article
- Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 1: In vivo small-animal imaging.Magnetic resonance in medicine · 2025Review
- Towards contrast-agnostic soft segmentation of the spinal cord.Medical image analysis · 2025Article
- LesionSCynth: A simple parametric lesion synthesis method to improve spinal cord lesion segmentation in low-data scenarios.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Body size and intracranial volume interact with the structure of the central nervous system: A multi-center in vivo neuroimaging study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Optimization of cervical cord atrophy measurement using a real-world, multicentre dataset in multiple sclerosis.Frontiers in neurology · 2025Article
- Microstructural Damage and Repair in the Spinal Cord of Patients With Early Multiple Sclerosis and Association With Disability at 5 Years.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Longitudinal reproducibility of brain and spinal cord quantitative MRI biomarkers.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Rootlets-based registration to the PAM50 spinal cord template.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Closing the diagnostic gap: A narrative review of recent advances in functional MRI diagnostics in spinal cord injury.Brain & spine · 2025Review
- Influence of scanning plane on Human Spinal Cord functional Magnetic Resonance echo planar imaging.PloS one · 2025Article
Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
91 authors.
Julien Cohen-AdadNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada. jcohen@polymtl.ca.ORCID http://orcid.org/0000-0003-3662-9532
Eva Alonso-OrtizNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Mihael AbramovicDepartment of Radiology, Swiss Paraplegic Centre, Nottwil, Switzerland.
Carina ArneitzDepartment of Radiology, Swiss Paraplegic Centre, Nottwil, Switzerland.
Nicole AtchesonCentre for Advanced Imaging, The University of Queensland, Brisbane, Australia.ORCID http://orcid.org/0000-0001-7075-1422
Laura BarlowDepartment of Radiology, University of British Columbia, Vancouver, BC, Canada.
Robert L BarryAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA.
Markus BarthSchool of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia.ORCID http://orcid.org/0000-0002-0520-1843
Marco BattistonNMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.
Christian BüchelDepartment of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0003-1965-906X
Matthew BuddeDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Virginie CallotAix-Marseille Univ, CNRS, CRMBM, Marseille, France.ORCID http://orcid.org/0000-0003-0850-1742
Anna J E CombesVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Benjamin De LeenerDepartment of Computer and Software Engineering, Polytechnique Montreal, Montreal, Canada.
Maxime DescoteauxCentre de Recherche CHUS, CIMS, Sherbrooke, Canada.
Paulo Loureiro de SousaUniversité de Strasbourg, CNRS, ICube, Strasbourg, France.ORCID http://orcid.org/0000-0001-6610-5997
Marek DostálUHB - University Hospital Brno and Masaryk University, Department of Radiology and Nuclear Medicine, Brno, Czech Republic.ORCID http://orcid.org/0000-0003-1740-9227
Julien DoyonMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.
Adam DvorakDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0001-6107-5610
Falk EippertMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Karla R EppersonRichard M. Lucas Center, Stanford University School of Medicine, Stanford, CA, USA.
Kevin S EppersonRichard M. Lucas Center, Stanford University School of Medicine, Stanford, CA, USA.
Patrick FreundSpinal Cord Injury Center Balgrist, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-4851-2246
Jürgen FinsterbuschDepartment of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Alexandru FoiasNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Michela FratiniInstitute of Nanotechnology, CNR, Rome, Italy.
Issei FukunagaDepartment of Radiology, Juntendo University School of Medicine, Tokyo, Japan.
Claudia A M Gandini Wheeler-KingshottNMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.
Giancarlo GermaniBrain MRI 3T Research Centre, IRCCS Mondino Foundation, Pavia, Italy.
Guillaume GilbertMR Clinical Science, Philips Healthcare, Markham, ON, Canada.
Federico GioveIRCCS Santa Lucia Foundation, Rome, Italy.ORCID http://orcid.org/0000-0002-6934-3146
Charley GrosNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.ORCID http://orcid.org/0000-0003-4318-0024
Francesco GrussuNMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.
Akifumi HagiwaraDepartment of Radiology, Juntendo University School of Medicine, Tokyo, Japan.
Pierre-Gilles HenryCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Tomáš HorákMultimodal and functional imaging laboratory, Central European Institute of Technology (CEITEC), Brno, Czech Republic.
Masaaki HoriDepartment of Radiology, Toho University Omori Medical Center, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1791-8032
James JoersCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-8444-2185
Kouhei KamiyaDepartment of Radiology, the University of Tokyo, Tokyo, Japan.
Haleh KarbasforoushanInterdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-2032-9703
Miloš KeřkovskýUHB - University Hospital Brno and Masaryk University, Department of Radiology and Nuclear Medicine, Brno, Czech Republic.
Ali KhatibiMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.ORCID http://orcid.org/0000-0003-0679-0499
Joo-Won KimBioMedical Engineering and Imaging Institute (BMEII), Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nawal KinanyInstitute of Bioengineering/Center for Neuroprosthetics, Ecole Polytechnique Fédérale de Lausanne, Geneva, Switzerland.
Hagen H KitzlerInstitute of Diagnostic and Interventional Neuroradiology, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0003-4749-1874
Shannon KolindDepartment of Radiology, University of British Columbia, Vancouver, BC, Canada.
Yazhuo KongCAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-8249-4723
Petr KudličkaMultimodal and functional imaging laboratory, Central European Institute of Technology (CEITEC), Brno, Czech Republic.ORCID http://orcid.org/0000-0002-3961-7986
Paul KuntkeInstitute of Diagnostic and Interventional Neuroradiology, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.
Nyoman D KurniawanCentre for Advanced Imaging, The University of Queensland, Brisbane, Australia.ORCID http://orcid.org/0000-0001-6340-182X
Slawomir KusmiaCUBRIC, Cardiff University, Wales, UK.
René LabounekDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0003-0439-1304
Maria Marcella LaganàIRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.ORCID http://orcid.org/0000-0001-7848-1711
Cornelia LauleDepartments of Radiology, Pathology & Laboratory Medicine, Physics & Astronomy; International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, Canada.
Christine S LawDivision of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-0524-6029
Christophe LengletCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0003-4646-3185
Tobias LeutritzDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.ORCID http://orcid.org/0000-0002-9871-4073
Yaou LiuDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Sara LlufriuCenter of Neuroimmunology, Laboratory of Advanced Imaging in Neuroimmunological Diseases, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Universitat de Barcelona, Barcelona, Spain.
Sean MackeyDivision of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Eloy Martinez-HerasCenter of Neuroimmunology, Laboratory of Advanced Imaging in Neuroimmunological Diseases, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Universitat de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0001-9937-3162
Loan MatteraFondation Campus Biotech Genève, 1202, Geneva, Switzerland.
Igor NestrasilCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, USA.ORCID http://orcid.org/0000-0002-3833-1484
Kristin P O'GradyVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-4550-2026
Nico PapinuttoUCSF Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Daniel PappNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Deborah ParetoNeuroradiology Section, Vall d'Hebron University Hospital, Barcelona, Spain.
Todd B ParrishInterdepartmental Neuroscience Program, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Anna PichiecchioDepartment of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy.
Ferran PradosNMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.ORCID http://orcid.org/0000-0002-7872-0142
Àlex RoviraNeuroradiology Section, Vall d'Hebron University Hospital, Barcelona, Spain.
Marc J RuitenbergSchool of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Australia.ORCID http://orcid.org/0000-0002-6917-0708
Rebecca S SamsonNMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.
Giovanni SaviniBrain MRI 3T Research Centre, IRCCS Mondino Foundation, Pavia, Italy.ORCID http://orcid.org/0000-0002-7133-429X
Maryam SeifSpinal Cord Injury Center Balgrist, University of Zurich, Zurich, Switzerland.
Alan C SeifertBioMedical Engineering and Imaging Institute (BMEII), Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alex K SmithWellcome Centre For Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Seth A SmithVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Zachary A SmithUniversity of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Elisabeth SolanaCenter of Neuroimmunology, Laboratory of Advanced Imaging in Neuroimmunological Diseases, Hospital Clinic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Universitat de Barcelona, Barcelona, Spain.
Y SuzukiDepartment of Radiology, the University of Tokyo, Tokyo, Japan.
George TackleyCUBRIC, Cardiff University, Wales, UK.ORCID http://orcid.org/0000-0002-7464-7662
Alexandra TinnermannDepartment of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jan ValošekDepartment of Neurology, Faculty of Medicine and Dentistry, Palacký University and University Hospital Olomouc, Olomouc, Czech Republic.ORCID http://orcid.org/0000-0002-7398-4990
Dimitri Van De VilleInstitute of Bioengineering/Center for Neuroprosthetics, Ecole Polytechnique Fédérale de Lausanne, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-2879-3861
Marios C YiannakasNMR Research Unit, Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK.
Kenneth A Weber IiDivision of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-0916-9174
Nikolaus WeiskopfDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.ORCID http://orcid.org/0000-0001-5239-1881
Richard G WiseCUBRIC, Cardiff University, Wales, UK.
Patrik O WyssDepartment of Radiology, Swiss Paraplegic Centre, Nottwil, Switzerland.
Junqian XuBioMedical Engineering and Imaging Institute (BMEII), Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Funding
Spinal cord functional connectivity as a biomarker of spinal cord dysfunctionR01EB027779 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BARRY, ROBERT L · 2019 to 2022
$2.7MNeuroimaging-Based Brain and Spinal Cord Biomarkers for Cervical RadiculopathyK23NS104211 · NINDS · STANFORD UNIVERSITY · PI WEBER, KENNETH ARNOLD · 2018 to 2022
$875kFunctional Imaging and resting state connectivity in human spinal cord at 7 TeslaR00EB016689 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BARRY, ROBERT L · 2016 to 2018
$747kEuropean Research Council
Abstract
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject dataset across 19 centers and a multi-subject dataset across 42 centers (for a total of 260 participants), spanning the three main MRI manufacturers: GE, Philips and Siemens. Both datasets are publicly available via git-annex. Data were analysed using the Spinal Cord Toolbox to produce normative values as well as inter/intra-site and inter/intra-manufacturer statistics. Reproducibility for the spine generic protocol was high across sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for all the metrics. Full documentation and results can be found at https://spine-generic.rtfd.io/ . The datasets and analysis pipeline will help pave the way towards accessible and reproducible quantitative MRI in the spinal cord.
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Magnetic Resonance ImagingNeuroimagingAdultFemaleHumansImage Processing, Computer-AssistedMaleReproducibility of ResultsSpinal Cord
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