ArticleNature communications2021
Toward scalable biocatalytic conversion of 5-hydroxymethylfurfural by galactose oxidase using coordinated reaction and enzyme engineering.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 104 citations in OpenAlex.
- Immobilized Hydroxymethylfurfural Oxidase Enables Robust Biocatalytic Production of 2,5-Furandicarboxylic Acid from Crude 5‑Hydroxymethylfurfural.ACS sustainable chemistry & engineering · 2026Article
- Using MD Simulations to Understand the Impact of Directed Evolution on Oxygen Affinity in Amine Oxidases.ChemistryOpen · 2026Article
- Crossing the Oxo-Peroxo Wall for Selective Electrochemical Epoxidation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Redox-Switchable Single-Atom Catalyst Enables Efficient Aqueous Hydroxymethylfurfural Oxidation.ACS catalysis · 2025Article
- Transforming a Historical Chemical Synthetic Route for Vanillin Starting from Renewable Eugenol to a Cell-Free Bi-Enzymatic Cascade.ChemSusChem · 2025Article
- Navigating Side Reactions for Robust Colorimetric Detection of Galactose Oxidase Activity.Analytical chemistry · 2025Article
- Stable and Promiscuous Galactose Oxidases Engineered by Directed Evolution, Atomistic Design, and Ancestral Sequence Reconstruction.ACS synthetic biology · 2025Article
- Facile Synthesis of a Novel Furanic Monomer and Its ADMET Polymerization toward Fully Renewable Functional Polymers.ACS sustainable chemistry & engineering · 2024Article
- Biocatalysis enables the scalable conversion of biobased furans into various furfurylamines.Nature communications · 2024Article
- In Situ Glycan Analysis and Editing in Living Systems.JACS Au · 2024Review
- Spectrophotometric Assay for the Detection of 2,5-Diformylfuran and Its Validation through Laccase-Mediated Oxidation of 5-Hydroxymethylfurfural.International journal of molecular sciences · 2023Article
- Operando generated copper-based catalyst enabling efficient electrosynthesis of 2,5-bis(hydroxymethyl)furan.Fundamental research · 2023Article
- Photocatalytic conversion of sugars to 5-hydroxymethylfurfural using aluminium(III) and fulvic acid.Nature communications · 2023Article
- Effect of Nitrogen, Air, and Oxygen on the Kinetic Stability of NAD(P)H Oxidase Exposed to a Gas-Liquid Interface.Organic process research & development · 2023Article
- A selective and atom-economic rearrangement of uridine by cascade biocatalysis for production of pseudouridine.Nature communications · 2023Article
- Review
- Copper-radical oxidases: A diverse group of biocatalysts with distinct properties and a broad range of biotechnological applications.Engineering microbiology · 2022Review
- Monitoring and control of the release of soluble OBiotechnology and bioengineering · 2022Article
- Hydrophilic Nonwoven Nanofiber Membranes as Nanostructured Supports for Enzyme Immobilization.ACS applied polymer materials · 2022Article
- Current Advances in the Sustainable Conversion of 5-Hydroxymethylfurfural into 2,5-Furandicarboxylic Acid.ChemSusChem · 2022Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
5-Hydroxymethylfurfural (HMF) has emerged as a crucial bio-based chemical building block in the drive towards developing materials from renewable resources, due to its direct preparation from sugars and its readily diversifiable scaffold. A key obstacle in transitioning to bio-based plastic production lies in meeting the necessary industrial production efficiency, particularly in the cost-effective conversion of HMF to valuable intermediates. Toward addressing the challenge of developing scalable technology for oxidizing crude HMF to more valuable chemicals, here we report coordinated reaction and enzyme engineering to provide a galactose oxidase (GOase) variant with remarkably high activity toward HMF, improved O
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.