Evidence map›Paper›PMID 34400544›Full record

ArticleJournal of clinical pathology2022

Not enough can be enough: feasibility of the Idylla

Cristiana Ercolani, Anna Di Benedetto, Claudia Bonomo, Paolo Visca, Aldo Palange, Daniela Assisi, Daniele Forcella, Irene Terrenato, Edoardo Pescarmona, Gennaro Ciliberto and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Cristiana ErcolaniPathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.ORCID http://orcid.org/0000-0003-0131-7766
Anna Di BenedettoPathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Claudia BonomoPathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Paolo ViscaPathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Aldo PalangePathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Daniela AssisiDepartment of Digestive Endoscopy, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Daniele ForcellaThoracic Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Irene TerrenatoBiostatistics-Scientific Direction, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Edoardo PescarmonaPathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Gennaro CilibertoScientific Direction, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Fabiana Letizia CecereDivision of Medical Oncology 1, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Federico CappuzzoDivision of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Simonetta BuglioniPathology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy simonetta.buglioni@ifo.gov.it.
Istituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe minimally invasive procedures used in the diagnostic workup of patients with advanced non-small cell lung cancer (NSCLC) often provide poor yields of pathological material suitable for molecular analyses. Not infrequently, the DNA yield from small biopsies/cytological samples is insufficient for the assessment of genomic biomarkers that inform personalised therapies. The Idylla

methodsTwenty NSCLC samples were selected accordingly to

resultsParallel assessment of

conclusionsIEMT can provide remarkable diagnostic accuracy for the assessment of

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsDNA Mutational AnalysisErbB ReceptorsFeasibility StudiesHumansMutationEGFR protein, humanErbB Receptorsdiagnostic techniques and proceduresDNAlung neoplasmsmolecular biology

Identifiers

PMID34400544
PMCPMC9685700
OpenAlexW3193897551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.