Evidence map›Paper›PMID 34400532›Full record

Trial reportLearning & memory (Cold Spring Harbor, N.Y.)2021

The effect of zolpidem on targeted memory reactivation during sleep.

Julia Carbone, Carlos Bibián, Patrick Reischl, Jan Born, Cecilia Forcato, Susanne Diekelmann

Open access · diamondAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Learning & memory (Cold Spring Harbor, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The GABANeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Julia CarboneInstitute of Medical Psychology and Behavioural Neurobiology, University of Tübingen, 72076 Tübingen, Germany.
Carlos BibiánInstitute of Medical Psychology and Behavioural Neurobiology, University of Tübingen, 72076 Tübingen, Germany.
Patrick ReischlInstitute of Medical Psychology and Behavioural Neurobiology, University of Tübingen, 72076 Tübingen, Germany.
Jan BornInstitute of Medical Psychology and Behavioural Neurobiology, University of Tübingen, 72076 Tübingen, Germany.
Cecilia ForcatoLaboratorio de Sueño y Memoria, Departamento de Ciencias de la Vida, Instituto Tecnológico de Buenos Aires (ITBA), Buenos Aires C1106ACD, Argentina.
Susanne DiekelmannInstitute of Medical Psychology and Behavioural Neurobiology, University of Tübingen, 72076 Tübingen, Germany.
University of Tübingen · DEConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the active system consolidation theory, memory consolidation during sleep relies on the reactivation of newly encoded memory representations. This reactivation is orchestrated by the interplay of sleep slow oscillations, spindles, and theta, which are in turn modulated by certain neurotransmitters like GABA to enable long-lasting plastic changes in the memory store. Here we asked whether the GABAergic system and associated changes in sleep oscillations are functionally related to memory reactivation during sleep. We administered the GABA

Indexed as

Memory ConsolidationSleepZolpidemElectroencephalographyHumansMemoryZolpidem

Identifiers

PMID34400532
PMCPMC8372567
OpenAlexW3195297665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.