ArticleProceedings of the National Academy of Sciences of the United States of America2021
Bindin is essential for fertilization in the sea urchin.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- The tuxedo sea urchinbioRxiv : the preprint server for biology · 2026Article
- Article
- Stable germline transgenesis using the Minos Tc1/mariner element in the sea urchin Lytechinus pictus.Development (Cambridge, England) · 2024Article
- The Effect of Synthetic Polyamine BPA-C8 on the Fertilization Process of Intact and Denuded Sea Urchin Eggs.Cells · 2024Article
- Conservation and contrast in cell states of echinoderm ovaries.Molecular reproduction and development · 2024Article
- Dithiothreitol Affects the Fertilization Response in Immature and Maturing Starfish Oocytes.Biomolecules · 2023Article
- Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries.Nature communications · 2023Article
- A case of hermaphroditism in the gonochoristic sea urchin, Strongylocentrotus purpuratus, reveals key mechanisms of sex determination†.Biology of reproduction · 2023Article
- Article
- Eukaryotic fertilization and gamete fusion at a glance.Journal of cell science · 2022Article
- Article
- Generation of a homozygous mutant drug transporter (ABCB1) knockout line in the sea urchin Lytechinus pictus.Development (Cambridge, England) · 2022Article
- Regulation of the Actin Cytoskeleton-Linked CaCells · 2022Article
- Cell-Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy.International journal of molecular sciences · 2022Review
- Article
- Recurrent Co-Option and Recombination of Cytokine and Three Finger Proteins in Multiple Reproductive Tissues Throughout Salamander Evolution.Frontiers in cell and developmental biology · 2022Article
- Editorial: Fertilization in the spotlight: Dynamics and mechanisms of sperm-egg interaction.Frontiers in cell and developmental biology · 2022Article
- Article
- Sperm lacking Bindin are infertile but are otherwise indistinguishable from wildtype sperm.Scientific reports · 2021Article
- A protein bridging the gap between sea urchin generations.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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4 authors.
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Abstract
Species-specific sperm-egg interactions are essential for sexual reproduction. Broadcast spawning of marine organisms is under particularly stringent conditions, since eggs released into the water column can be exposed to multiple different sperm. Bindin isolated from the sperm acrosome results in insoluble particles that cause homospecific eggs to aggregate, whereas no aggregation occurs with heterospecific eggs. Therefore, Bindin is concluded to play a critical role in fertilization, yet its function has never been tested. Here we report that Cas9-mediated inactivation of the
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