Evidence map›Paper›PMID 34400361›Full record

ArticleContemporary clinical trials2021

Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The "PRONE" Study.

Eugene Friedman, John Franzone, Emily R Ko, Kristin Corey, Jason Mock, Naseem Alavian, Adam Schwartz, M Bradley Drummond, Tomeka Suber, Kelsey Linstrum and 7 more

Open access · greenAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Eugene FriedmanDuke University, Division of Pulmonary, Allergy, and Critical Care Medicine, DUMC Box 102352, Durham, NC 27710, United States of America.
John FranzoneDuke University, Division of Hospital Medicine, Department of General Internal Medicine, Durham, NC 27710, United States of America.
Emily R KoDuke University, Division of Hospital Medicine, Department of General Internal Medicine, Durham, NC 27710, United States of America.
Kristin CoreyDuke University, Division of Pulmonary, Allergy, and Critical Care Medicine, DUMC Box 102352, Durham, NC 27710, United States of America.
Jason MockUniversity of North Carolina, Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, 130 Mason Farm Road, CB# 7020, 4(th) floor Bioinformatics Bldg, Chapel Hill, NC 27599-7020, United States of America.
Naseem AlavianUniversity of North Carolina, Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, 130 Mason Farm Road, CB# 7020, 4(th) floor Bioinformatics Bldg, Chapel Hill, NC 27599-7020, United States of America.
Adam SchwartzUniversity of North Carolina, Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, 130 Mason Farm Road, CB# 7020, 4(th) floor Bioinformatics Bldg, Chapel Hill, NC 27599-7020, United States of America.
M Bradley DrummondUniversity of North Carolina, Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, 130 Mason Farm Road, CB# 7020, 4(th) floor Bioinformatics Bldg, Chapel Hill, NC 27599-7020, United States of America.
Tomeka SuberUniversity of Pittsburgh, Division of Pulmonary, Allergy, and Critical Care Medicine, 3459 Fifth Avenue, Montefiore NW628, Pittsburgh, PA 15213, United States of America.
Kelsey LinstrumUniversity of Pittsburgh, Division of Pulmonary, Allergy, and Critical Care Medicine, 3459 Fifth Avenue, Montefiore NW628, Pittsburgh, PA 15213, United States of America.
William BainUniversity of Pittsburgh, Division of Pulmonary, Allergy, and Critical Care Medicine, 3459 Fifth Avenue, Montefiore NW628, Pittsburgh, PA 15213, United States of America.
Saramaria Afanador CastiblancoUniversity of Miami, Division of Pulmonary, Critical Care and Sleep Medicine, University of Miami Miller School Of Medicine, 1951 NW 7th Ave, 2nd Floor, Room 2278, Miami, FL 33136, United States of America.
Martin ZakUniversity of Miami, Division of Pulmonary, Critical Care and Sleep Medicine, University of Miami Miller School Of Medicine, 1951 NW 7th Ave, 2nd Floor, Room 2278, Miami, FL 33136, United States of America.
Sandra ZaehJohns Hopkins University, Division of Pulmonary And Critical Care Medicine, 5501 Hopkins Baview Cr., JHAAC, Room 4A.30, Baltimore, MD 21224, United States of America.
Ishaan GuptaJohns Hopkins University, Division of Pulmonary And Critical Care Medicine, 5501 Hopkins Baview Cr., JHAAC, Room 4A.30, Baltimore, MD 21224, United States of America.
Mahendra DamarlaJohns Hopkins University, Division of Pulmonary And Critical Care Medicine, 5501 Hopkins Baview Cr., JHAAC, Room 4A.30, Baltimore, MD 21224, United States of America. Electronic address: mdamarl1@jhmi.edu.
Naresh M PunjabiUniversity of Miami, Division of Pulmonary, Critical Care and Sleep Medicine, University of Miami Miller School Of Medicine, 1951 NW 7th Ave, 2nd Floor, Room 2278, Miami, FL 33136, United States of America.
Johns Hopkins University · USUniversity of Miami · USUniversity of Pittsburgh · USDuke University · USDuke University Hospital · US

Funding

Defining the Role of Regulatory T Cells in Resolution of Acute Lung InjuryR01HL152077 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOCK, JASON ROBERT · 2021 to 2025
$2.9M
Regulatory T Cells Promote Alveolar Epithelial RepairK08HL129075 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOCK, JASON ROBERT · 2016 to 2019
$685k
Defining the Role of Regulatory T Cell-Derived MMP12 in Acute Lung Injury ResolutionR03HL145255 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MOCK, JASON ROBERT · 2018 to 2019
$156k
NHLBI NIH HHS K08 HL129075NHLBI NIH HHS R01 HL152077NHLBI NIH HHS R03 HL145255
6 · The paper itself

Abstract

While benefits of prone position in mechanically-ventilated patients have been well-described, a randomized-control trial to determine the effects of prone positioning in awake, spontaneously-breathing patients with an acute pneumonia has not been previously conducted. Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts: the "PRONE" Study (PRONE) was conducted in non-intubated hospitalized patients with coronavirus disease 2019 (COVID-19) pneumonia as defined by respiratory rate ≥ 20/min or an oxyhemoglobin saturation (SpO

Indexed as

COVID-19HumansPatient PositioningProne PositionRandomized Controlled Trials as TopicRespiration, ArtificialSARS-CoV-2AwakeCOVID-19HospitalizedMulticenterProneRandomized

Identifiers

PMID34400361
PMCPMC8363159
OpenAlexW3194904660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.