Evidence map›Paper›PMID 34400138›Full record

ArticleBiochimica et biophysica acta. Biomembranes2021

Calcium-induced release of cytochrome c from cardiolipin nanodisks: Implications for apoptosis.

Colin A Fox, Kyle Lethcoe, Robert O Ryan

Open access · greenAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Alkaline State of the Domain-Swapped Dimer of Human CytochromeJournal of the American Chemical Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Colin A FoxDepartment of Biochemistry and Molecular Biology, University of Nevada, Reno, Reno, NV 89557, United States of America.
Kyle LethcoeDepartment of Biochemistry and Molecular Biology, University of Nevada, Reno, Reno, NV 89557, United States of America.
Robert O RyanDepartment of Biochemistry and Molecular Biology, University of Nevada, Reno, Reno, NV 89557, United States of America. Electronic address: robertryan@unr.edu.
University of Nevada, Reno · US

Funding

Effect of Apolipoprotein Structural AdaptabilityR37HL064159 · NHLBI · UNIVERSITY OF NEVADA RENO · PI RYAN, ROBERT O'MARA · 2010 to 2019
$4.1M
NHLBI NIH HHS R37 HL064159
6 · The paper itself

Abstract

Miniature bilayer membranes comprised of phospholipid and an apolipoprotein scaffold, termed nanodisks (ND), have been used in binding studies. When ND formulated with cardiolipin (CL), but not phosphatidylcholine, were incubated with cytochrome c, FPLC gel filtration chromatography provided evidence of a stable binding interaction. Incubation of CL ND with CaCl

Indexed as

AnimalsApolipoproteinsApoptosisBinding SitesCalciumCalcium ChlorideCardiolipinsCell CommunicationCytochromes cLipid BilayersLocusta migratoriaMitochondrial MembranesPhagocytosisPhospholipidsProtein BindingProtein DomainsApolipoproteinsCalciumCalcium ChlorideCardiolipinsCytochromes cLipid BilayersPhospholipidsApoptosisCalciumCardiolipinCytochrome cNanodisk

Identifiers

PMID34400138
PMCPMC8464532
OpenAlexW3193468373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.