Evidence map›Paper›PMID 34399715›Full record

ArticleBMC psychiatry2021

Sleep problems in children with autism spectrum disorder: a multicenter survey.

Hongyu Chen, Ting Yang, Jie Chen, Li Chen, Ying Dai, Jie Zhang, Ling Li, Feiyong Jia, Lijie Wu, Yan Hao and 9 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 1 country.

Hongyu ChenChildren's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Childhood Nutrition and Health, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Ting YangChildren's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Childhood Nutrition and Health, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Jie ChenChildren's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Childhood Nutrition and Health, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Li ChenChildren's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Childhood Nutrition and Health, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Ying DaiChildren's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Childhood Nutrition and Health, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.
Jie ZhangXi'an Children's Hospital, Xi'an, 710003, China.
Ling LiDepartment of Children Rehabilitation, Hainan Women and Children's Medical Center, Haikou, 570100, China.
Feiyong JiaDepartment of Developmental and Behavioral Pediatric, the First Hospital of Jilin University, Changchun, 130021, China.
Lijie WuDepartment of Children's and Adolescent Health, Public Health College of Harbin Medical University, Harbin, 150081, China.
Yan HaoDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Xiaoyan KeChild mental health research center of Nanjing Brain Hospital, Nanjing, 210013, China.
Mingji YiDepartment of Child Health Care, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Qi HongMaternal and Child Health Hospital of Baoan, Shenzhen, 518133, China.
Jinjin ChenDepartment of Child Healthcare, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, 200040, China.
Shuanfeng FangChildren's Hospital Affiliated to Zhengzhou University, Zhengzhou, 450053, China.
Yichao WangNHC Key Laboratory of Birth Defect for Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, 410008, China.
Qi WangDeyang Maternity & Child Healthcare Hospital, Deyang, 618000, Sichuan, China.
Chunhua JinDepartment of Children Health Care, Capital Institute of Pediatrics, Beijing, 100020, China.
Tingyu LiChildren's Hospital of Chongqing Medical University, Chongqing Key Laboratory of Childhood Nutrition and Health, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China. tyli@vip.sina.com.
Chongqing Medical University · CNChildren's Hospital of Chongqing Medical University · CNCapital Institute of Pediatrics · CNFirst Hospital of Jilin University · CNHarbin Medical University · CNHunan Provincial Maternal and Child Health Hospital · CNMaternal and Child Health Care Hospital of Bao'an · CNMaternal and Child Health Hospital of Sichuan Province · CNNanjing Brain Hospital · CNQingdao University · CNShanghai Jiao Tong University · CNTongji Hospital · CNXi’an Children’s Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh prevalence of sleep problems have been reported in children with Autism Spectrum Disorder (ASD). This study aims to investigate the sleep conditions of ASD children in China, and explore the relationship between the common sleep problems and core symptoms and developmental levels.

methodsUsing a cross-sectional design, we included 2 to 7-year-old children from 13 cities in China: 1310 with ASD and 1158 with typically-developing (TD) children. The neurodevelopmental level was evaluated with the revised Children Neuropsychological and Behavior Scale (CNBS-R2016). ASD were diagnosed with DSM-5 and Child Autism Rating Scale (CARS). the Social Responsiveness Scale (SRS), the Autism Behavior Checklist (ABC) and the communication warning behavior sub-scale in CNBS-R2016 valued autism behaviors. The children' s sleep habits questionnaire (CSHQ) assessed sleep conditions.

resultsThe prevalence of sleep disorders in ASD children was significantly higher than that in TD (67.4% vs. 51%, p < 0.01), and among them the four dimensions with the highest prevalence of sleep problems were bedtime resistance (25.6%), sleep anxiety (22.7%), sleep onset delay (17.9%) and daytime sleepiness (14.7%). ASD children with sleep onset delay or sleep anxiety had higher ABC, SRS scores and higher scores on communication warning behavior with sleep anxiety, with daytime sleepiness had higher ABC, SRS and CARS scores, and with bedtime resistance had higher SRS total scores. Differences in the neurodevelopmental level were not significant.

conclusionChildren with ASD have a higher prevalence of sleep problems. Bedtime resistance, anxiety, sleep onset delay and daytime sleepiness may be related to the core symptoms, but not be related to the developmental level in ASD children. In the clinic, sleep assessment should be included in the routine of ASD visits, and during the intervention, sleep hygiene education is as important as the treatment of biological factors.

trial registrationThe study was approved by the ethics committee of the Children's Hospital of Chongqing Medical University, Approval Number: (2018) IRB (STUDY) NO. 121, and registered in the Chinese Clinical Trial Registry (Registration number: ChiCTR2000031194 ).

Indexed as

Autism Spectrum DisorderSleep Wake DisordersChildChild, PreschoolCross-Sectional StudiesHumansSleepSurveys and QuestionnairesASDChildrenMulticenterSleep hygieneSleep problems

Identifiers

PMID34399715
PMCPMC8365936
OpenAlexW3193828778

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.