Evidence map›Paper›PMID 34399580›Full record

ArticleCirculation research2021

Heart and Brain Pericytes Exhibit a Pro-Fibrotic Response After Vascular Injury.

Thanh T D Pham, Shuin Park, Kamal Kolluri, Riki Kawaguchi, Lingjun Wang, Dana Tran, Peng Zhao, S Thomas Carmichael, Reza Ardehali

Abstract readLetter
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Single-cell RNA sequencing in stroke and traumatic brain injury: Current achievements, challenges and future perspectives on transcriptomic profiling.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  4. Article
  5. Pericytes in tissue fibrosis.American journal of physiology. Cell physiology · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Pericytes in the disease spotlight.Trends in cell biology · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thanh T D Pham *Cardiology, Internal Medicine (S.P., K.K., L.W., P.Z., R.A.).
Shuin Park *Molecular, Cellular and Integrative Physiology Graduate Program (T.T.D.P., S.P., S.T.C., R.A.).
Kamal Kolluri *Cardiology, Internal Medicine (S.P., K.K., L.W., P.Z., R.A.).
Riki KawaguchiNeurology, David Geffen School of Medicine, UCLA (T.T.D.P., R.K., D.T., S.T.C.).
Lingjun WangCardiology, Internal Medicine (S.P., K.K., L.W., P.Z., R.A.).ORCID 0000-0003-1535-4170
Dana TranNeurology, David Geffen School of Medicine, UCLA (T.T.D.P., R.K., D.T., S.T.C.).
Peng ZhaoCardiology, Internal Medicine (S.P., K.K., L.W., P.Z., R.A.).
S Thomas CarmichaelNeurology, David Geffen School of Medicine, UCLA (T.T.D.P., R.K., D.T., S.T.C.).ORCID 0000-0002-1169-9203
Reza ArdehaliCardiology, Internal Medicine (S.P., K.K., L.W., P.Z., R.A.).ORCID 0000-0003-1318-4016

Funding

The role of pericytes in scar formation following stroke and myocardial infarctionR01NS112256 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CARMICHAEL, STANLEY THOMAS · 2020 to 2024
$2.2M
UCLA Neuroscience Physician-Scientist Training ProgramUE5NS065723 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Stanley Thomas Carmichael, Jason D Hinman · 2024 to 2026
$1.2M
NINDS NIH HHS R01 NS112256NINDS NIH HHS UE5 NS065723
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

TranscriptomeAnimalsBrainCell Adhesion MoleculesCollagenFibrosisMiceMyocardial InfarctionMyocardiumPericytesCell Adhesion MoleculesCollagenPostn protein, mousebrainfibrosisheartischemic strokemyocardial infarctionpericytes

Identifiers

PMID34399580
PMCPMC8448975

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.