Evidence map›Paper›PMID 34399137›Full record

ArticleDrug and alcohol dependence2021

Assessment of transient dopamine responses to smoked cannabis.

Katina C Calakos, Heather Liu, Yihuan Lu, Jon Mikael Anderson, David Matuskey, Nabeel Nabulsi, Yunpeng Ye, Patrick D Skosnik, Deepak Cyril D'Souza, Evan D Morris and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Modeling PET Data Acquired During Nonsteady Conditions: What If Brain Conditions Change During the Scan?Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Review
  2. Psychotomimetic compensation versus sensitization.Pharmacology research & perspectives · 2024
    Review
  3. Novel voxelwise residual analysis of [Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Katina C CalakosDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Interdepartmental Neuroscience Program, Yale University, 333 Cedar Street, New Haven, CT, 06510, United States. Electronic address: katina.calakos@yale.edu.
Heather LiuDepartment of Biomedical Engineering, Yale University, 17 Hillhouse Avenue, New Haven, CT, 06511, United States. Electronic address: heather.liu@yale.edu.
Yihuan LuDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Yale PET Center, Yale University, 801 Howard Avenue, New Haven, CT, 06510, United States. Electronic address: yihuan.lu@yale.edu.
Jon Mikael AndersonDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States. Electronic address: jonmikael.anderson@yale.edu.
David MatuskeyDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Yale PET Center, Yale University, 801 Howard Avenue, New Haven, CT, 06510, United States; Department of Neurology, Yale School of Medicine, 800 Howard Avenue, New Haven, CT, 06519, United States. Electronic address: david.matuskey@yale.edu.
Nabeel NabulsiDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Yale PET Center, Yale University, 801 Howard Avenue, New Haven, CT, 06510, United States. Electronic address: nabeel.nabulsi@yale.edu.
Yunpeng YeDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Yale PET Center, Yale University, 801 Howard Avenue, New Haven, CT, 06510, United States. Electronic address: yunpeng.ye@yale.edu.
Patrick D SkosnikDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, 34 Park Street, New Haven, CT, 06519, United States. Electronic address: patrick.skosnik@yale.edu.
Deepak Cyril D'SouzaDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, 34 Park Street, New Haven, CT, 06519, United States. Electronic address: deepak.dsouza@yale.edu.
Evan D MorrisDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Interdepartmental Neuroscience Program, Yale University, 333 Cedar Street, New Haven, CT, 06510, United States; Department of Biomedical Engineering, Yale University, 17 Hillhouse Avenue, New Haven, CT, 06511, United States; Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Yale PET Center, Yale University, 801 Howard Avenue, New Haven, CT, 06510, United States. Electronic address: evan.morris@yale.edu.
Kelly P CosgroveDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Interdepartmental Neuroscience Program, Yale University, 333 Cedar Street, New Haven, CT, 06510, United States; Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Department of Neuroscience, Yale University, 333 Cedar Street, New Haven, CT, 06510, United States. Electronic address: kelly.cosgrove@yale.edu.
Ansel T HillmerDepartment of Psychiatry, Yale School of Medicine, 300 George Street, New Haven, CT, 06511, United States; Department of Biomedical Engineering, Yale University, 17 Hillhouse Avenue, New Haven, CT, 06511, United States; Department of Radiology and Biomedical Imaging, Yale School of Medicine, 330 Cedar Street, New Haven, CT, 06519, United States; Yale PET Center, Yale University, 801 Howard Avenue, New Haven, CT, 06510, United States. Electronic address: ansel.hillmer@yale.edu.
Yale University · USYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Interdepartmental Neuroscience Program (INP)T32NS041228 · NINDS · YALE UNIVERSITY · PI Charles A Greer, Marina R Picciotto · 2001 to 2026
$12.0M
Imaging Molecular Mechanisms of Tobacco Smoking WithdrawalR01DA038832 · NIDA · YALE UNIVERSITY · PI COSGROVE, KELLY P. · 2016 to 2021
$3.6M
Multimodal Neuroimaging of Alcohol Withdrawal: The Role of Glutamate in Neural ReorganizationK01AA024788 · NIAAA · YALE UNIVERSITY · PI HILLMER, ANSEL · 2017 to 2021
$894k
Imaging the Opioid Response to Cannabis SmokingR03DA047588 · NIDA · YALE UNIVERSITY · PI HILLMER, ANSEL · 2019 to 2019
$251k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K01 AA024788NIDA NIH HHS R01 DA038832NIDA NIH HHS R03 DA047588NINDS NIH HHS T32 NS041228
6 · The paper itself

Abstract

backgroundDopaminergic mechanisms that may underlie cannabis' reinforcing effects are not well elucidated in humans. This positron emission tomography (PET) imaging study used the dopamine D

methodsPET emission data were acquired from regular cannabis users (n = 14; 7 M/7 F; 19-32 years old) over 90 min immediately after [

resultsCannabis smoking increased plasma Δ

conclusionsThese preliminary data support the sensitivity of [

Indexed as

CannabisMarijuana SmokingVentral StriatumAdultCorpus StriatumDopamineHumansPositron-Emission TomographyRacloprideYoung AdultDopamineRaclopride[(11)C]racloprideCannabisDopaminePET

Identifiers

PMID34399137
PMCPMC8464527
OpenAlexW3189702438

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.