Evidence map›Paper›PMID 34399033›Full record

ReviewChemSusChem2021

Laccase as a Tool in Building Advanced Lignin-Based Materials.

Melissa B Agustin, Danila Morais de Carvalho, Maarit H Lahtinen, Kristiina Hilden, Taina Lundell, Kirsi S Mikkonen

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ChemSusChem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
21.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 138 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Research Progress of Laccase in Edible and Medicinal Fungi.Journal of fungi (Basel, Switzerland) · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Interfacial Properties of Surface-Modified Lignin Nanoparticles.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Melissa B AgustinDepartment of Food and Nutrition, Faculty of Agriculture and Forestry, University of Helsinki, 00014, Helsinki, Finland.
Danila Morais de CarvalhoDepartment of Food and Nutrition, Faculty of Agriculture and Forestry, University of Helsinki, 00014, Helsinki, Finland.
Maarit H LahtinenDepartment of Food and Nutrition, Faculty of Agriculture and Forestry, University of Helsinki, 00014, Helsinki, Finland.
Kristiina HildenDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, 00014, Helsinki, Finland.
Taina LundellDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, 00014, Helsinki, Finland.
Kirsi S MikkonenDepartment of Food and Nutrition, Faculty of Agriculture and Forestry, University of Helsinki, 00014, Helsinki, Finland.
University of Helsinki · FIHelsinki Institute of Physics · FI

Funding

Academy of Finland PickPollutants PostDoc Project 330617AromaFung project 297847European Commission through the European Research Council PARTIFACE 863808Jane and Aatos Erkko Foundation GOOD project
6 · The paper itself

Abstract

Lignin is an abundant natural feedstock that offers great potential as a renewable substitute for fossil-based resources. Its polyaromatic structure and unique properties have attracted significant research efforts. The advantages of an enzymatic over chemical or thermal approach to construct or deconstruct lignins are that it operates in mild conditions, requires less energy, and usually uses non-toxic chemicals. Laccase is a widely investigated oxidative enzyme that can catalyze the polymerization and depolymerization of lignin. Its dual nature causes a challenge in controlling the overall direction of lignin-laccase catalysis. In this Review, the factors that affect laccase-catalyzed lignin polymerization were summarized, evaluated, and compared to identify key features that favor lignin polymerization. In addition, a critical assessment of the conditions that enable production of novel lignin hybrids via laccase-catalyzed grafting was presented. To assess the industrial relevance of laccase-assisted lignin valorization, patented applications were surveyed and industrial challenges and opportunities were analyzed. Finally, our perspective in realizing the full potential of laccase in building lignin-based materials for advanced applications was deduced from analysis of the limitations governing laccase-assisted lignin polymerization and grafting.

Indexed as

enzyme catalysisgraftinglaccaseligninpolymerization

Identifiers

PMID34399033
PMCPMC8597079
OpenAlexW3194417623

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.