Evidence map›Paper›PMID 34398670›Full record

ArticleAntimicrobial agents and chemotherapy2021

Elevated MICs of Susceptible Antipseudomonal Cephalosporins in Non-Carbapenemase-Producing, Carbapenem-Resistant Pseudomonas aeruginosa: Implications for Dose Optimization.

Christian M Gill, Elif Aktaş, Wadha Alfouzan, Lori Bourassa, Adrian Brink, Carey-Ann D Burnham, Rafael Canton, Yehuda Carmeli, Marco Falcone, Carlos Kiffer and 9 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Global epidemiology of carbapenem-resistantJAC-antimicrobial resistance · 2026
    Review
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Christian M GillCenter for Anti-Infective Research & Development, Hartford Hospitalgrid.277313.3, Hartford, Connecticut, USA.
Elif AktaşUniversity of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Clinical Microbiology Laboratory, Istanbul, Turkey.
Wadha AlfouzanLaboratory Medicine, Farwaniya Hospital, Ministry of Health, Kuwait City, Kuwait.
Lori BourassaDepartment of Laboratory Medicine and Pathology, University of Washingtongrid.34477.33, Seattle, Washington, USA.ORCID 0000-0001-8903-5274
Adrian BrinkDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, National Health Laboratory Services, University of Cape Town, Cape Town, South Africa.
Carey-Ann D BurnhamWashington University in St. Louis, School of Medicine, St. Louis, Missouri, USA.
Rafael CantonServicio de Microbiologia, Hospital Ramón y Cajal-IRYCIS, Madrid, Spain.ORCID 0000-0003-1675-3173
Yehuda CarmeliNational Institute for Infection Control and Antibiotic Resistance, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Marco FalconeInfectious Diseases Division, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Carlos KifferInternal Medicine Department and LEMC, Alerta Lab, Escola Paulista de Medicina, UNIFESP, São Paulo, Brazil.
Anna MarcheseDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Octavio MartinezDepartment of Pathology and Microbiology, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Spyros PournarasLaboratory of Clinical Microbiology, School of Medicine, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Harald SeifertInstitute for Medical Microbiology, Immunology and Hygiene, University of Colognegrid.6190.e, Cologne, Germany.
Abrar K ThabitPharmacy Practice Department, Faculty of Pharmacy, King Abdulaziz Universitygrid.412125.1, Jeddah, Saudi Arabia.ORCID 0000-0002-0369-9094
Maria Virginia VillegasGrupo de Resistencia Antimicrobiana y Epidemiología Hospitalaria (RAEH), Universidad El Bosque, Bogotá, Colombia.
Lars F WestbladeDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA.
David P NicolauCenter for Anti-Infective Research & Development, Hartford Hospitalgrid.277313.3, Hartford, Connecticut, USA.ORCID 0000-0002-4148-0165
ERACE-PA Global Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study evaluated the

Indexed as

CephalosporinsPseudomonas InfectionsAnti-Bacterial AgentsAzabicyclo CompoundsCarbapenemsCeftazidimeHumansMicrobial Sensitivity TestsPseudomonas aeruginosaAnti-Bacterial AgentsAzabicyclo CompoundsCarbapenemsCeftazidimeCephalosporinscarbapenem resistancecefepimeceftazidimepharmacodynamicspharmacokineticsPseudomonas aeruginosa

Identifiers

PMID34398670
PMCPMC8522773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.