ArticleChemSusChem2021
Green Fabrication Approaches of Lignin Nanoparticles from Different Technical Lignins: A Comparison Study.
Article in ChemSusChem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 106 citations in OpenAlex.
- Gallate-oriented surface engineering of lignin nanoparticles for enhanced antibacterial activity.Materials today. Bio · 2026Article
- Magnetic nanoparticles as promising materials for the future of medicine.Journal of materials science. Materials in medicine · 2026Review
- Modulating the Spontaneous Adsorption of Lignin Nanoparticle at Oil-Water Interfaces.Macromolecular rapid communications · 2025Article
- Article
- Optimizing the lignin nanoparticles from different pulping by-products in developing cotton-based nanocrystalline cellulose for UV‑light blocking.Scientific reports · 2025Article
- Spontaneous and Laccase-Assisted Adsorption of Hemicelluloses Rendering Colloidal Stability of Lignin Nanoparticles at Low pH.ChemSusChem · 2025Article
- Machine learning techniques for lipid nanoparticle formulation.Nano convergence · 2025Review
- Interfacial Properties of Surface-Modified Lignin Nanoparticles.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Optimized and Functionalized Carvacrol-Loaded Nanostructured Lipid Carriers for Enhanced Cytotoxicity in Breast Cancer Cells.Pharmaceutics · 2025Article
- Lignin Ultrafiltration Fractionation and Self-Assembly to Monodisperse Nanoparticles for Photonic Materials.ACS omega · 2025Article
- Lignin nanoparticles in food packaging: a sustainable approach to material design and performance enhancement.Frontiers in nutrition · 2025Review
- Article
- Review
- Overcoming Challenges of Lignin Nanoparticles: Expanding Opportunities for Scalable and Multifunctional Nanomaterials.Accounts of chemical research · 2024Article
- Lignins as Promising Renewable Biopolymers and Bioactive Compounds for High-Performance Materials.Polymers · 2023Review
- Lignocellulosic Bionanomaterials for Biosensor Applications.Micromachines · 2023Review
- Newly Synthesized Lignin Microparticles as Bioinspired Oral Drug-Delivery Vehicles: Flavonoid-Carrier Potential and In Vitro Radical-Scavenging Activity.Pharmaceutics · 2023Article
- Biobased Nanomaterials─The Role of Interfacial Interactions for Advanced Materials.Chemical reviews · 2023Review
- Lignin nanoparticles as co-stabilizers and modifiers of nanocellulose-based Pickering emulsions and foams.Cellulose (London, England) · 2023Article
- Stabilized Lignin Nanoparticles for Versatile Hybrid and Functional Nanomaterials.Biomacromolecules · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
The production of lignin nanoparticles (LNPs) has emerged as a way to overcome the highly variable and complex molecular structure of lignin. It can offer morphological control of the lignin polymer, allowing the formation of stable LNP dispersions in aqueous media, while increasing the potential of lignin for high-value applications. However, the polydispersity and morphology of LNPs varies depending on the lignin grade and preparation method, and a systematic comparison using different technical lignins is lacking. In this study, it was attempted to find a green fabrication method with a distinct solvent fractionation of lignin to prepare LNPs using three different technical lignins as starting polymers: BLN birch lignin (hardwood, BB), alkali Protobind 1000 (grass, PB), and kraft LignoBoost (softwood, LB). For that, three anti-solvent precipitation approaches to prepare LNPs were systematically compared: 70 % aqueous ethanol, acetone/water (3 : 1) and NaOH as the lignin solvent, and water/aqueous HCl as the anti-solvent. Among all these methods, the acetone/water (3 : 1) approach allowed production of homogeneous and monodisperse LNPs with a negative surface charge and also spherical and smooth surfaces. Overall, the results revealed that the acetone/water (3 : 1) method was the most effective approach tested to obtain homogenous, small, and spherical LNPs from the three technical lignins. These LNPs exhibited an improved stability at different ionic strengths and a wider pH range compared to the other preparation methods, which can greatly increase their application in many fields, such as pharmaceutical and food sciences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.