ReviewCurrent heart failure reports2021
Echocardiographic Longitudinal Strain Analysis in Heart Failure: Real Usefulness for Clinical Management Beyond Diagnostic Value and Prognostic Correlations? A Comprehensive Review.
Review in Current heart failure reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Left and Right Atrial Strain Across the Heart Failure Continuum: Multifaceted Markers of Subclinical Mechanical Dysfunction and Haemodynamic Burden.Diagnostics (Basel, Switzerland) · 2026Review
- Usefulness of Strain Echocardiography in Heart Failure with Preserved Ejection Fraction.Journal of clinical medicine · 2026Review
- Improvement initiatives in the diagnostic process of heart failure: a scoping review.Frontiers in cardiovascular medicine · 2025Review
- Assessment of new-onset heart failure prediction in a diabetic population using left ventricular global strain: a prospective cohort study based on UK Biobank.Frontiers in endocrinology · 2024Article
- Path to Accurate and Universal Strain Measurement: Insights From a Validation Study.Journal of cardiovascular imaging · 2023Article
- Childhood Cancer Survivors Have Impaired Strain-Derived Myocardial Contractile Reserve by Dobutamine Stress Echocardiography.Journal of clinical medicine · 2023Article
- Echocardiographic strategy for early detection of cardiotoxicity of doxorubicin: a prospective observational study.Cardio-oncology (London, England) · 2022Article
- Left atrial remodeling in heart failure: the role of sphericity index (the SPHERICAT-HF study).The international journal of cardiovascular imaging · 2022Article
- Machine learning algorithm using publicly available echo database for simplified "visual estimation" of left ventricular ejection fraction.World journal of experimental medicine · 2022Article
- Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report.Frontiers in cardiovascular medicine · 2022Article
- Subclinical dysfunction of remote myocardium is related to high NT-proBNP and affects global contractility at follow-up, independently of infarct area.Frontiers in cardiovascular medicine · 2022Article
- Effects of Hypertrophic and Dilated Cardiac Geometric Remodeling on Ejection Fraction.Frontiers in physiology · 2022Article
- Review
- Prognostic value of temporal patterns of global longitudinal strain in patients with chronic heart failure.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart failure (HF) is a highly prevalent clinical syndrome characterized by considerable phenotypic heterogeneity. The traditional classification based on left ventricular ejection fraction (LVEF) is widely accepted by the guidelines and represents the grounds for patient enrollment in clinical trials, even though it shows several limitations. Ejection fraction (EF) is affected by preload, afterload, and contractility, it being problematic to express LV function in several conditions, such as HF with preserved EF (HFpEF), valvular heart disease, and subclinical HF, and in athletes. Over the last two decades, developments in diagnostic techniques have provided useful tools to overcome EF limitations. Strain imaging analysis (particularly global longitudinal strain (GLS)) has emerged as a useful echocardiographic technique in patients with HF, as it is able to simultaneously supply information on both systolic and diastolic functions, depending on cardiac anatomy and physiology/pathophysiology. The use of GLS has proved helpful in terms of diagnostic performance and prognostic value in several HF studies. Universally accepted cutoff values and variability across vendors remain an area to be fully explored, hence limiting routine application of this technique in clinical practice. In the present review, the current role of GLS in the diagnosis and management of patients with HF will be discussed. We describe, by critical analysis of the pros and cons, various clinical settings in HF, and how the appropriate use and interpretation of GLS can provide important clues.
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Registered trials
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