ReviewNano-micro letters2021
Recent Progress in Nanoscale Covalent Organic Frameworks for Cancer Diagnosis and Therapy.
Review in Nano-micro letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Fluorinated pore walls boost PFAS capture in mechanochemically synthesized covalent organic frameworks.RSC advances · 2026Article
- Smart covalent organic frameworks in cancer sensing and imaging: opportunities, challenges, and translational prospects.Medical oncology (Northwood, London, England) · 2026Review
- Reprogramming Lung Redox Homeostasis by NIR Driven Ultra-Small Pd Loaded Covalent Organic Framework Inhibits NF-κB Pathway for Acute Lung Injury Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Nanotechnology in healthcare, and its safety and environmental risks.Journal of nanobiotechnology · 2024Review
- Covalent-Organic Framework-Based Materials in Theranostic Applications: Insights into Their Advantages and Challenges.ACS omega · 2024Review
- Fe-HCOF-PEGInternational journal of nanomedicine · 2024Article
- Covalent organic framework-based nanoplatforms with tunable mechanical properties for drug delivery and cancer therapy.Mechanobiology in medicine · 2023Review
- Biomedical Approach of Nanotechnology and Biological Risks: A Mini-Review.International journal of molecular sciences · 2023Review
- Review
- Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications.Bioactive materials · 2023Review
- Covalent Organic Framework Nanobowls as Activatable Nanosensitizers for Tumor-Specific and Ferroptosis-Augmented Sonodynamic Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Review
- Nanomedicine Strategies for Heating "Cold" Ovarian Cancer (OC): Next Evolution in Immunotherapy of OC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- Highly stable β-ketoenamine-based covalent organic frameworks (COFs): synthesis and optoelectrical applications.Frontiers of optoelectronics · 2022Review
- Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy.Nano-micro letters · 2022Review
- Emerging early diagnostic methods for acute kidney injury.Theranostics · 2022Review
- Emerging Bismuth Chalcogenides Based Nanodrugs for Cancer Radiotherapy.Frontiers in pharmacology · 2022Review
- Thiadiazoloquinoxaline-Based Semiconducting Polymer Nanoparticles for NIR-II Fluorescence Imaging-Guided Photothermal Therapy.Frontiers in bioengineering and biotechnology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Covalent organic frameworks (COFs) as a type of porous and crystalline covalent organic polymer are built up from covalently linked and periodically arranged organic molecules. Their precise assembly, well-defined coordination network, and tunable porosity endow COFs with diverse characteristics such as low density, high crystallinity, porous structure, and large specific-surface area, as well as versatile functions and active sites that can be tuned at molecular and atomic level. These unique properties make them excellent candidate materials for biomedical applications, such as drug delivery, diagnostic imaging, and disease therapy. To realize these functions, the components, dimensions, and guest molecule loading into COFs have a great influence on their performance in various applications. In this review, we first introduce the influence of dimensions, building blocks, and synthetic conditions on the chemical stability, pore structure, and chemical interaction with guest molecules of COFs. Next, the applications of COFs in cancer diagnosis and therapy are summarized. Finally, some challenges for COFs in cancer therapy are noted and the problems to be solved in the future are proposed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.