Evidence map›Paper›PMID 34398296›Full record

ArticlePediatric surgery international2021

Skip segment Hirschsprung's disease: report of two rare cases and management.

Hong Yang, Yangyang Ma, Shaobo Yang, Yanlei Huang, Gong Chen

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Surgical pathology of Hirschsprung disease (HSCR).World journal of pediatric surgery · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hong YangDepartment of Surgery, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai, 201102, China.
Yangyang MaDepartment of Pathology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai, 201102, China.
Shaobo YangDepartment of Surgery, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai, 201102, China. ysb8479@163.com.ORCID http://orcid.org/0000-0003-1642-605X
Yanlei HuangDepartment of Surgery, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai, 201102, China.
Gong ChenDepartment of Surgery, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai, 201102, China.
Children's Hospital of Fudan University · CN

Funding

national natural science foundation of china 81801498shanghai municipal health bureau (cn) 20174Y0018shanghai "rising stars of medical talent" youth development program 2019-72
6 · The paper itself

Abstract

purposeSkip segment Hirschsprung's disease (SS-HSCR) is defined as the occurrence of a segment of ganglionated intestine surrounded proximally and distally by aganglionosis. The presence of the skip intestinal segment often leads to clinical misdiagnosis, missed diagnosis or inadequate resection of the lesions. The purpose was to describe two new cases of SS-HSCR with the aim of proposing questions regarding the diagnosis and treatment of this rare disease.

methodsWe reported two cases of infants with SS-HSCR that were admitted to our institution within the last 3 years.

resultsOne patient had a skip segment of ganglionated intestine in the ascending colon. In the other patient, there were no ganglionic cells in the rectum and appendix, but ganglionic cells were visible in the proximal ascending colon. The entire colons in the both cases were finally resected, and a pull-through operation was performed.

conclusionMultipoint biopsy should be performed when the biopsy results are inconsistent with clinical manifestations. Intraoperative laparoscopic identification of the transition zone may be necessary when TCA is suspected. Multisegment biopsy is needed to as a preventative measure for SS-HSCR if TCA is indicated during surgery. Further study is required to determine the optimal length and method of retention of segments.

Indexed as

Hirschsprung DiseaseLaparoscopyBiopsyHumansInfantRectumAganglionosisHirschsprung’s diseasePull-through operationRectal suction biopsySkip segment

Identifiers

PMID34398296
OpenAlexW3194549031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.