ArticleRheumatology (Oxford, England)2022
Comparison of salivary gland MRI and ultrasonography findings among patients with Sjögren's syndrome over a wide age range.
Article in Rheumatology (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Role of Major Salivary Gland MRI in Adult Sjögren's Disease: Protocols, Findings, and Clinical Utility.Cureus · 2026Review
- Proposal for a new staging system of Sjögren's syndrome using salivary gland SPECT/CT: comparison with Saxon test, MR sialography, and histopathological examination.Oral radiology · 2026Article
- Evaluation of salivary gland changes in menopausal women with xerostomia using the modified Schirmer test and ultrasonography.BMC oral health · 2026Article
- Multidimensional assessment of Juvenile Sjögren disease.Clinical rheumatology · 2025Article
- Recent Advances in Pathogenesis, Diagnostic Imaging, and Treatment of Sjögren's Syndrome.Journal of clinical medicine · 2024Article
- Salivary gland ultrasound elastography requires interpretation of "normal".Laryngoscope investigative otolaryngology · 2024Article
- A Case of Pediatric Sjögren's Syndrome Diagnosed With Microcalcifications in Both Parotid Glands.Cureus · 2024Article
- Imaging the Micron: New Directions in Diagnosis with Ultra-High-Frequency Ultrasound.Diagnostics (Basel, Switzerland) · 2024Article
- Three Signs to Help Detect Sjögren's Syndrome: Incidental Findings on Magnetic Resonance Imaging and Computed Tomography.Journal of clinical medicine · 2023Article
- A comparative study of three-dimensional cone-beam CT sialography and MR sialography for the detection of non-tumorous salivary pathologies.BMC oral health · 2023Article
- Diagnostic Evaluation Using Salivary Gland Ultrasonography in Primary Sjögren's Syndrome.Journal of clinical medicine · 2023Article
- Imaging Findings of Pediatric Rheumatic Disorders: JIA in the PRINTO Era and Autoimmune Interferonopathies.Pediatrics international : official journal of the Japan Pediatric SocietyReview
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis retrospective study compared MRI and US findings among patients with SS over a wide age range.
methodsNinety patients with SS aged 8-84 years who had undergone both MRI and US examinations were divided into four groups according to age, as follows: <18 years (juvenile SS, JSS), 9 patients; 18-39 years, 12 patients; 40-69 years, 53 patients; >69 years, 16 patients. Imaging findings of parotid glands (PGs) and submandibular glands (SMGs) were compared among the four groups. Furthermore, the relationships within and between imaging findings and various clinical findings were examined.
resultsOn MRI, patients with JSS commonly exhibited multiple high-intensity spots in the PGs on MR sialography and fat-suppressed T2-weighted imaging. With increasing SS group age, the frequencies and numbers of the high-intensity spots were lower. Fat areas on MRI and hyperechoic bands on US were rarely observed in the PGs and SMGs of patients with JSS, whereas they were more common in patients with adult SS. In addition, the presence of hyperechoic bands on US, the presence of fat areas on MRI, and decreased salivary flow were associated with one another.
conclusionSalivary gland imaging findings in patients with JSS were characterized by punctate sialectasis, whereas those findings in patients with adult SS were characterized by fatty degeneration. Distinct findings in patients with JSS and adult SS are likely to reflect differences in glandular lesion stage. MRI and US are presumably useful for evaluation of glandular lesion severity during follow-up.
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