Evidence map›Paper›PMID 34397577›Full record

ReviewCurrent opinion in ophthalmology2021

Description and management of retinopathy of prematurity reactivation after intravitreal antivascular endothelial growth factor therapy.

Nita G Valikodath, Michael F Chiang, R V Paul Chan

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Dysregulation of histone deacetylases in ocular diseases.Archives of pharmacal research · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Nita G ValikodathDepartment of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois.
Michael F ChiangNational Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
R V Paul ChanDepartment of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois.
Monterey Bay Aquarium Foundation · USNational Eye Institute · USUniversity of Illinois Chicago · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4M
Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MCANANY, JAMES JASON · 1985 to 2025
$14.8M
Clinical and Genetic Analysis of Retinopathy of PrematurityR01EY019474 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2010 to 2020
$7.0M
Nonmydriatic ultra-widefield fundus photography employing trans-pars-planar illuminationR01EY029673 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHAN, ROBISON VERNON PAUL, YAO, XINCHENG · 2019 to 2022
$1.8M
Clinical and genetic analysis of retinopathy of prematurityR01HD107493 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2021 to 2023
$1.8M
Intramural NIH HHS Z99 EY999999NEI NIH HHS P30 EY001792NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY019474NEI NIH HHS R01 EY029673NICHD NIH HHS R01 HD107493
6 · The paper itself

Abstract

purpose of reviewTo review the literature regarding reactivation of retinopathy of prematurity (ROP) after treatment with antivascular endothelial growth factor (anti-VEGF) agents. RECENT

findingsReactivation can occur after anti-VEGF or laser. Risk factors for reactivation include patient and disease-related factors. Various studies are evaluating the use of different anti-VEGF agents and reactivation rates. However, the definition of reactivation varies between studies. SUMMARY: The literature has varied definitions of reactivation, which is often used interchangeably with recurrence. It is important to recognize features of reactivation of ROP to appropriately manage patients and conduct clinical trials. The International Classification of ROP 3rd edition has established a consensus guideline regarding terminology describing reactivation.

Indexed as

Angiogenesis InhibitorsBevacizumabEndothelial Growth FactorsHumansInfant, NewbornIntravitreal InjectionsLaser CoagulationPractice Guidelines as TopicRecurrenceRetinopathy of PrematurityTerminology as TopicVascular Endothelial Growth Factor AAngiogenesis InhibitorsBevacizumabEndothelial Growth FactorsVascular Endothelial Growth Factor A

Identifiers

PMID34397577
PMCPMC8514167
OpenAlexW3191347054

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.