ArticleJournal of developmental and behavioral pediatrics : JDBP2021
Co-Occurrence of Neurodevelopmental Disorders in Pediatric Sickle Cell Disease.
Article in Journal of developmental and behavioral pediatrics : JDBP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Academic and cerebrovascular outcomes after neurodevelopmental screening in sickle cell disease: A longitudinal cohort study.Developmental medicine and child neurology · 2026Article
- Associations Between Sickle Cell Disease, Pica, and Enuresis in Pediatric Neurodevelopmental Disorders.Medical sciences (Basel, Switzerland) · 2026Article
- Comorbid ADHD and Pediatric Sickle Cell Disease: Prevalence and Risk Factors.Journal of clinical psychology in medical settings · 2025Article
- Greig cephalopolysyndactyly contiguous gene syndrome in a Congolese patient co-occurring with sickle cell anemia, and review of literature.Clinical dysmorphology · 2025Article
- Current developmental screening practices in young children with sickle cell disease.British journal of haematology · 2023Article
- Subanesthetic ketamine: the way forward for pain management in sickle cell disease patients?Expert review of hematology · 2022Article
- Developmental disorders in children born to women with sickle cell disease: A report from the Boston Birth Cohort.EJHaem · 2022Article
- Imaging Blood-Brain Barrier Permeability Through MRI in Pediatric Sickle Cell Disease: A Feasibility Study.Journal of magnetic resonance imaging : JMRI · 2022Article
- Sluggish Cognitive Tempo in Pediatric Sickle Cell Disease.Frontiers in neurology · 2022Article
- Brain Oxygen Extraction and Metabolism in Pediatric Patients With Sickle Cell Disease: Comparison of Four Calibration Models.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe objective of this study is to retrospectively determine the co-occurrence, associated characteristics, and risk factors for neurodevelopmental disorders (NDD) in a pediatric sickle cell disease (SCD) clinic population.
methodWe investigated the co-occurrence and features of NDD in pediatric SCD through a retrospective cohort study conducted between July 2017 and January 2019. The participants were patients with SCD younger than 18 years of age identified from our institutions' clinic rosters and medical records databases.
resultsA total of 276 participants were eligible for study inclusion, and 65 participants were found to have various NDD. Children with SCD and NDD were more likely to have a history of multiple SCD-related complications in comparison to children with SCD without NDD. Children with SCD and NDD were more likely to use disease-modifying therapies in comparison to children with SCD without NDD (χ2 27.2, p < 0.001).
conclusionChildren with SCD and NDD have higher odds of having certain disease-related complications and higher use of disease-modifying treatments than children with SCD who do not have NDD. Screening and diagnoses of NDD may be relevant to clinical management of pediatric SCD.
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Registered trials
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