Evidence map›Paper›PMID 34397173›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Aquaporin-Incorporated Graphene-Oxide Membrane for Pressurized Desalination with Superior Integrity Enabled by Molecular Recognition.

Chang Seon Lee, Insu Kim, Jae Won Jang, Dae Sung Yoon, Yun Jung Lee

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chang Seon LeeDepartment of Energy Engineering, Hanyang University, Seoul, 04763, Republic of Korea.
Insu KimSchool of Biomedical Engineering, Korea University, Seoul, 02841, Republic of Korea.
Jae Won JangSchool of Biomedical Engineering, Korea University, Seoul, 02841, Republic of Korea.ORCID 0000-0003-4105-9001
Dae Sung YoonSchool of Biomedical Engineering, Korea University, Seoul, 02841, Republic of Korea.
Yun Jung LeeDepartment of Energy Engineering, Hanyang University, Seoul, 04763, Republic of Korea.ORCID 0000-0003-3091-1174
Korea University · KRHanyang University · KR

Funding

Korea Toray Science Foundation: Science and Technology GrantNational Research Foundation of Korea, Ministry of Science and ICT NRF-2019R1A2B5B01070617National Research Foundation of Korea, Ministry of Science and ICT NRF- 2021R1A2C2006170
6 · The paper itself

Abstract

Aquaporins (AQPs), the natural water channel, have been actively investigated for overcoming the limitations of conventional desalination membranes. An AQP-based biomimetic high-pressure desalination membrane is designed by tethering AQP-carrying red blood cell membrane (RBCM) vesicles onto graphene oxide (GO). RBCMs with AQPs are incorporated into GO based on the molecular recognition between the integrin of RBCM and Arginine-Glycine-Aspartate (RGD) ligand on the GO surface. GO is pre-functionalized with the Glycine-Arginine-Glycine-Aspartate-Serine peptide to capture RBCMs. RBCMs are inserted between GO flakes through the material-specific interaction between integrin of RBCM and RGD ligand, thus ensuring sufficient coverage of channels/defects in the GO for the full functioning of the AQPs. The incorporated AQPs are not completely fixed at the GO, as tethering is mediated by the integrin-RGD pair, and suitable AQP flexibility for appropriate functioning is guaranteed without frictional hindrance from the solid substrate. The integrity of the GO-RBCMs binding can provide mechanical strength for enduring high-pressure reverse-osmosis conditions for treating large amounts of water. This biomimetic membrane exhibits 99.1% NaCl rejection and a water permeance of 7.83 L m

Indexed as

AquaporinsArginineAspartic AcidBiomimeticsCell MembraneErythrocytesFiltrationGlycineGraphiteHumansIntegrinsSodium ChlorideWaterAquaporinsArginineAspartic AcidGlycinegraphene oxideGraphiteIntegrinsSodium ChlorideWateraquaporinbiomimeticgraphene oxidemembranesmolecular recognition

Identifiers

PMID34397173
PMCPMC8529452
OpenAlexW3194699600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.