Evidence map›Paper›PMID 34397086›Full record

ReviewBioscience reports2021

The reproductive tract microbiota in pregnancy.

Karen Grewal, David A MacIntyre, Phillip R Bennett

Open access · goldAbstract readReview
In one paragraph

Review in Bioscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Karen GrewalTommy's National Centre for Miscarriage Research, Hammersmith Hospital Campus, Du Cane Road, London, U.K.ORCID 0000-0002-1443-7364
David A MacIntyreTommy's National Centre for Miscarriage Research, Hammersmith Hospital Campus, Du Cane Road, London, U.K.
Phillip R BennettTommy's National Centre for Miscarriage Research, Hammersmith Hospital Campus, Du Cane Road, London, U.K.
Hammersmith Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reproductive tract microbiota plays a crucial role in maintenance of normal pregnancy and influences reproductive outcomes. Microbe-host interactions in pregnancy remain poorly understood and their role in shaping immune modulation is still being uncovered. In this review, we describe the composition of vaginal microbial communities in the reproductive tract and their association with reproductive outcomes. We also consider strategies for manipulating microbiota composition by using live biotherapeutics, selective eradication of pathogenic bacteria with antibiotics and vaginal microbiota transplantation. Finally, future developments in this field and the need for mechanistic studies to explore the functional significance of reproductive tract microbial communities are highlighted.

Indexed as

MicrobiotaReproductionAnimalsAnti-Bacterial AgentsBacteriaBiological TherapyDysbiosisFemaleHost-Pathogen InteractionsHumansPregnancyPregnancy Complications, InfectiousPregnancy OutcomeVaginaVaginosis, BacterialAnti-Bacterial AgentsMicrobiotaPregnancyReproduction

Identifiers

PMID34397086
PMCPMC8421591
OpenAlexW3195347176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.