Evidence map›Paper›PMID 34396718›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

3D Printed Wesselsite Nanosheets Functionalized Scaffold Facilitates NIR-II Photothermal Therapy and Vascularized Bone Regeneration.

Chen Yang, Hongshi Ma, Zhiyong Wang, Muhammad Rizwan Younis, Chunyang Liu, Chengtie Wu, Yongxiang Luo, Peng Huang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 158 citations in OpenAlex.

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  16. Bioactive Inorganic Materials for Innervated Multi-Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chen YangMarshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Hongshi MaState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai, 200050, China.
Zhiyong WangMarshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Muhammad Rizwan YounisMarshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Chunyang LiuMarshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Chengtie WuState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai, 200050, China.
Yongxiang LuoMarshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, China.
Peng HuangMarshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, 518060, China.ORCID 0000-0003-3651-7813
Shenzhen University Health Science Center · CNChinese Academy of Sciences · CN

Funding

Basic Research Program of Shenzhen JCYJ20170412111100742Basic Research Program of Shenzhen JCYJ20180507182413022Basic Research Program of Shenzhen JCYJ20200109105620482National Key R&D Program of China 2018YFA0704000National Key R&D Program of China 2020YFA0908800National Natural Science Foundation of China 21807074National Natural Science Foundation of China 31900945Shanghai Rising-Star Program 21QA1410500Shenzhen Science and Technology Program KQTD20190929172538530Youth Innovation Promotion Association CAS 2021249
6 · The paper itself

Abstract

Various bifunctional scaffolds have recently been developed to address the reconstruction of tumor-initiated bone defects. Such scaffolds are usually composed of a near-infrared (NIR) photothermal conversion agent and a conventional bone scaffold for photothermal therapy (PTT) and long-term bone regeneration. However, the reported photothermal conversion agents are mainly restricted to the first biological window (NIR-I) with intrinsic poor tissue penetration depth. Also, most of these agents are non-bioactive materials, which induced potential systemic side toxicity after implantation. Herein, a NIR-II photothermal conversion agent (Wesselsite [SrCuSi

Indexed as

Tissue EngineeringAnimalsBiocompatible MaterialsBone NeoplasmsBone RegenerationCell DifferentiationCell ProliferationHumansHuman Umbilical Vein Endothelial CellsMaleMesenchymal Stem CellsNanostructuresOsteogenesisPhotothermal TherapyPolyestersPrinting, Three-DimensionalBiocompatible MaterialspolycaprolactonePolyestersangiogenesisNIR-IIosteogenesisphotothermal therapyvascularized bone regeneration

Identifiers

PMID34396718
PMCPMC8529444
OpenAlexW3195702463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.