Evidence map›Paper›PMID 34396410›Full record

ReviewThe Journal of infectious diseases2021

Gonococcal Pelvic Inflammatory Disease: Placing Mechanistic Insights Into the Context of Clinical and Epidemiological Observations.

Stacey X Xu, Scott D Gray-Owen

Abstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Frontiers in microbiology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Efficacy and classification ofFrontiers in chemistry · 2024
    Article
  8. Review
  9. Article
  10. New insights intoFrontiers in cellular and infection microbiology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stacey X XuDepartment of Molecular Genetics, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Scott D Gray-OwenDepartment of Molecular Genetics, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1477-3616

Funding

Using gonococcal TonB-dependent transporters as vaccine antigensU19AI144182 · NIAID · GEORGIA STATE UNIVERSITY · PI CORNELISSEN, CYNTHIA N · 2019 to 2023
$9.3M
Gonococcal Vaccine Evaluation in a Humanized Mouse ModelR01AI103400 · NIAID · BOSTON MEDICAL CENTER · PI WETZLER, LEE MARK · 2013 to 2020
$5.2M
NIAID NIH HHS R01 AI103400NIAID NIH HHS U19 AI144182
6 · The paper itself

Abstract

While infection by Neisseria gonorrhoeae is often asymptomatic in women, undetected infections can ascend into the upper genital tract to elicit an inflammatory response that manifests as pelvic inflammatory disease, with the outcomes depending on the intensity and duration of inflammation and whether it is localized to the endometrial, fallopian tube, ovarian, and/or other tissues. This review examines the contribution of N. gonorrhoeae versus other potential causes of pelvic inflammatory disease by considering new insights gained through molecular, immunological, and microbiome-based analyses, and the current epidemiological burden of infection, with an aim to highlighting key areas for future study.

Indexed as

Chlamydia InfectionsEndometritisEndometriumFallopian TubesFemaleGonorrheaHumansNeisseria gonorrhoeaePelvic Inflammatory Diseasecervicitisendometrial infectionendometritisgonorrheaNeisseria gonorrhoeaeneutrophiloophoritispelvic inflammatory disease (PID)salpingitis

Identifiers

PMID34396410
PMCPMC8365115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.