Evidence map›Paper›PMID 34396398›Full record

ReviewThe Journal of infectious diseases2021

A Review of the Challenges and Complexities in the Diagnosis, Etiology, Epidemiology, and Pathogenesis of Pelvic Inflammatory Disease.

Sharon L Hillier, Kyle T Bernstein, Sevgi Aral

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. PreconceptionmedRxiv : the preprint server for health sciences · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. AFrontiers in immunology · 2026
    Article
  13. Long-Term Dynamics of Pelvic Inflammatory Disease Attributable toInternational journal of women's health · 2026
    Article
  14. Limited Role ofObstetrics and gynecology international · 2026
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sharon L HillierDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh and the Magee-Womens Research Institute, Pittsburgh, Pennsylvania, USA.
Kyle T BernsteinCenters for Disease Control and Prevention, Division of STD Prevention, Atlanta, Georgia, USA.
Sevgi AralCenters for Disease Control and Prevention, Division of STD Prevention, Atlanta, Georgia, USA.
Centers for Disease Control and Prevention · USUniversity of Pittsburgh · US

Funding

University of North Carolina - Chlamydia Vaccine Initiative (UNC-CVI)U19AI144181 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DARVILLE, TONI · 2019 to 2023
$10.7M
NIAID NIH HHS U19 AI144181
6 · The paper itself

Abstract

Pelvic inflammatory disease (PID) is a syndrome that causes substantial morbidity, including chronic pelvic pain, to women globally. While limited data are available from low- and middle-income countries, national databases from the United States and Europe suggest that PID incidence may be decreasing but the rate of decrease may differ by the etiologic cause. Recent studies of women with PID have reported that fewer than half of women receiving a diagnosis of PID have gonococcal or chlamydial infection, while Mycoplasma genitalium, respiratory pathogens, and the constellation of bacteria associated with bacterial vaginosis may account for a substantial fraction of PID cases. The clinical diagnosis of PID is nonspecific, creating an urgent need to develop noninvasive tests to diagnose PID. Advances in serologic testing for Chlamydia trachomatis and Neisseria gonorrhoeae could advance epidemiologic studies, while the development of vaccines against these sexually transmitted pathogens could affect incident PID and associated morbidity.

Indexed as

Pelvic Inflammatory DiseaseChlamydia InfectionsChlamydia trachomatisFemaleGonorrheaHumansIncidenceNeisseria gonorrhoeaeUnited Statesbacterial vaginosisChlamydiaendometritisgonorrheaMycoplasma genitaliumPID

Identifiers

PMID34396398
PMCPMC8365114
OpenAlexW3193833744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.