Evidence map›Paper›PMID 34396382›Full record

ArticleChemical communications (Cambridge, England)2021

NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance.

Lucille Babel, Minh-Ha Nguyen, Cédric Mittelheisser, Marie Martin, Katharina M Fromm, Olivier Walker, Maggy Hologne

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucille BabelUniversity of Fribourg, Department of Chemistry, chemin du musée 9, Fribourg 1700, Switzerland.
Minh-Ha Nguyen
Cédric Mittelheisser
Marie Martin
Katharina M Fromm
Olivier Walker
Maggy Hologne

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SilE and SilB are both proteins involved in the silver efflux pump found in Gram-negative bacteria such as S. typhimurium. Using model peptides along with NMR and CD experiments, we show how SilE may store silver ions prior to delivery and we hypothesize for the first time the interplay between SilB and SilE.

Indexed as

Amino Acid SequenceBacterial ProteinsBinding SitesCarrier ProteinsDrug Resistance, BacterialNuclear Magnetic Resonance, BiomolecularPeptide FragmentsProtein BindingSalmonella typhimuriumSilverBacterial ProteinsCarrier ProteinsPeptide FragmentsSilE protein, Salmonella typhimuriumSilver

Identifiers

PMID34396382
PMCPMC8686694

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.