Evidence map›Paper›PMID 34396333›Full record

ArticleJACC. CardioOncology2021

Vo

Raheel Rizwan, Kimberlee Gauvreau, Cheryl Vinograd, Jessica M Yamada, Christina Mangano, Andrea K Ng, Mark E Alexander, Ming Hui Chen

Open access · goldAbstract read
In one paragraph

Article in JACC. CardioOncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Childhood cancer and future cardiometabolic health.npj metabolic health and disease · 2026
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Raheel RizwanDepartment of Pediatrics, Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA.
Kimberlee GauvreauDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Cheryl VinogradDepartment of Pediatrics, New York University Grossman School of Medicine, New York, New York, USA.
Jessica M YamadaDepartment of Pediatrics, Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA.
Christina ManganoDepartment of Pediatrics, Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA.
Andrea K NgDepartment of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Mark E AlexanderDepartment of Cardiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Ming Hui ChenDepartment of Pediatrics, Division of Genetics and Genomics, Boston Children's Hospital, Boston, Massachusetts, USA.
Boston Children's Hospital · USBrigham and Women's Hospital · USNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdult survivors of Hodgkin lymphoma (HL) are at increased risk of cardiovascular (CV) events secondary to mediastinal radiation therapy (RT).

objectivesIn this group of patients, we assessed the association between cardiopulmonary exercise testing (CPET), as determined by percent-predicted peak Vo

methodsAll survivors of HL who were >10 years post chest RT and who underwent ≥1 CPET were enrolled from a single center. Traditional CV and treatment risk factors, along with CV events, were ascertained.

resultsA total of 64 patients (67% female; median age 51 years [range 26 to 70 years]) with a median follow-up time after RT of 23 years (range 11 to 41 years), and 141 CPET studies, were included. Median initial ppVo

conclusionsPercent-predicted Vo

Indexed as

BCH, Boston Children’s Hospitalcardiac eventscardiopulmonary testCPET, cardiopulmonary exercise testingCV, cardiovascularHL, Hodgkin lymphomaHodgkin lymphomaLSM, least squares meanppVo2peak, percent-predicted peak volume oxygenradiationRER, respiratory exchange ratioRT, radiation therapysexVo2women

Identifiers

PMID34396333
PMCPMC8352271
OpenAlexW3166003410

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.