Evidence map›Paper›PMID 34396303›Full record

ReviewJACC. CardioOncology2021

BSE and BCOS Guideline for Transthoracic Echocardiographic Assessment of Adult Cancer Patients Receiving Anthracyclines and/or Trastuzumab.

Rebecca Dobson, Arjun K Ghosh, Bonnie Ky, Tom Marwick, Martin Stout, Allan Harkness, Rick Steeds, Shaun Robinson, David Oxborough, David Adlam and 13 more

Open access · goldAbstract readReview
In one paragraph

Review in JACC. CardioOncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Cancer in pregnancy: FIGO Best practice advice and narrative review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Cardio-Oncology and Multi-Imaging Modalities.Journal of clinical medicine · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 18 institutions in 3 countries.

Rebecca DobsonCardio-Oncology Service, Liverpool Heart and Chest NHS Foundation Trust, Liverpool, United Kingdom.
Arjun K GhoshCardio-Oncology Service, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Bonnie KyPerelman School of Medicine at the University of Pennsylvania, Philadelphia, USA.
Tom MarwickBaker Heart and Diabetes Institute, Melbourne, Australia.
Martin StoutUniversity Hospital South Manchester NHS Foundation Trust, Manchester, United Kingdom.
Allan HarknessEast Suffolk and North Essex NHS Foundation Trust, Colchester, United Kingdom.
Rick SteedsUniversity Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Shaun RobinsonNorth West Anglia Foundation Trust, United Kingdom.
David OxboroughLiverpool John Moores University, Liverpool, United Kingdom.
David AdlamUniversity Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Susannah StanwayRoyal Marsden NHS Foundation Trust and Institute of Cancer Research, London, United Kingdom.
Bushra RanaImperial College Healthcare NHS Trust, London, United Kingdom.
Thomas IngramThe Shrewsbury and Telford Hospital NHS Trust, Shrewsbury, United Kingdom.
Liam RingWest Suffolk NHS Foundation Trust, Bury St. Edmunds, United Kingdom.
Stuart RosenRoyal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom.
Chris PlummerThe Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom.
Charlotte ManistyCardio-Oncology Service, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom.
Mark HarbinsonBelfast Health and Social Care Trust, Belfast, United Kingdom.
Vishal SharmaRoyal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, United Kingdom.
Keith PearceUniversity Hospital South Manchester NHS Foundation Trust, Manchester, United Kingdom.
Alexander R LyonRoyal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom.
Daniel X AugustineDepartment of Cardiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom.
British Society of Echocardiography (BSE) and theBritish Society of Cardio-Oncology (BCOS)
Manchester University NHS Foundation Trust · GBRoyal Brompton & Harefield NHS Foundation Trust · GBBaker Heart and Diabetes Institute · AUBarts Health NHS Trust · GBBelfast Health and Social Care Trust · GBEast Suffolk and North Essex NHS Foundation Trust · GBImperial College Healthcare NHS Trust · GBLiverpool John Moores University · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBRoyal Liverpool and Broadgreen University Hospital NHS Trust · GBRoyal Marsden NHS Foundation Trust · GBRoyal United Hospital Bath NHS Trust · GBShrewsbury and Telford Hospital NHS Trust · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity Hospitals of Leicester NHS Trust · GBUniversity of Pennsylvania · USWest Suffolk NHS Foundation Trust · GB

Funding

British Heart Foundation FS/CRTF/21/24134
6 · The paper itself

Abstract

The subspecialty of cardio-oncology aims to reduce cardiovascular morbidity and mortality in patients with cancer or following cancer treatment. Cancer therapy can lead to a variety of cardiovascular complications, including left ventricular systolic dysfunction, pericardial disease, and valvular heart disease. Echocardiography is a key diagnostic imaging tool in the diagnosis and surveillance for many of these complications. The baseline assessment and subsequent surveillance of patients undergoing treatment with anthracyclines and/or human epidermal growth factor receptor (HER) 2-positive targeted treatment (e.g., trastuzumab and pertuzumab) form a significant proportion of cardio-oncology patients undergoing echocardiography. This guideline from the British Society of Echocardiography and British Cardio-Oncology Society outlines a protocol for baseline and surveillance echocardiography of patients undergoing treatment with anthracyclines and/or trastuzumab. The methodology for acquisition of images and the advantages and disadvantages of techniques are discussed. Echocardiographic definitions for considering cancer therapeutics-related cardiac dysfunction are also presented.

Indexed as

2D, 2-dimensional3D, 3-dimensionalA2C, apical 2-chamberA3C, apical 3-chamberA4C, apical 4-chamberanthracyclineBSE, British Society of EchocardiographyCMR, cardiac magnetic resonanceCTRCD, cancer therapy–related cardiac dysfunctionECG, electrocardiogramechocardiographyGLS, global longitudinal strainguidelinesHER2, human epidermal growth factor receptor 2HER2 therapyimagingLVEF, left ventricular ejection fractionLV, left ventricularMV, mitral valveRH, right heartROI, region of interestRV, right ventricularTDI, tissue Doppler imagingTRV, tricuspid regurgitant velocity

Identifiers

PMID34396303
PMCPMC8352267
OpenAlexW3136930884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.