Evidence map›Paper›PMID 34396141›Full record

ArticleCritical care explorations2021

Psychologic Distress and Quality of Life After ICU Treatment for Coronavirus Disease 2019: A Multicenter, Observational Cohort Study.

Johan H Vlake, Jasper Van Bommel, Merel E Hellemons, Evert-Jan Wils, O Joseph Bienvenu, Anna F C Schut, Eva Klijn, Marten P Van Bavel, Diederik Gommers, Michel E Van Genderen

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. COVID-19-related health utility values and changes in COVID-19 patients and the general population: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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  11. One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived COVID-19.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Johan H VlakeDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Jasper Van BommelDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Merel E HellemonsDepartment of Pulmonology, Erasmus Medical Center, Rotterdam, the Netherlands.
Evert-Jan WilsDepartment of Intensive Care, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.
O Joseph BienvenuDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.
Anna F C SchutDepartment of Intensive Care, Ikazia Hospital, Rotterdam, the Netherlands.
Eva KlijnDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Marten P Van BavelDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Diederik GommersDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Michel E Van GenderenDepartment of Intensive Care, Erasmus Medical Center, Rotterdam, the Netherlands.
Erasmus MC · NLSint Franciscus Gasthuis · NLIkazia Ziekenhuis · NLJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To quantify short- and long-term psychologic distress, that is, symptoms of posttraumatic stress disorder, anxiety, and depression, and the health-related quality of life in coronavirus disease 2019 ICU survivors.

designA prospective, observational cohort study.

settingPostcoronavirus disease 2019 clinics of three hospitals in Rotterdam, the Netherlands. PATIENTS: Adult patients admitted for coronavirus disease 2019 to the ICU, who visited the postcoronavirus disease 2019 follow-up clinic. MEASURES AND MAIN

resultsThe primary outcomes were psychologic distress and overall and mental health-related quality of life, assessed using the Impact of Event Scale-Revised, Hospital Anxiety and Depression Scale, Short-Form 36, and European Quality of Life 5D, 6 weeks, 3 months, and 6 months post hospital discharge. Second, we compared 3-month psychologic and mental health-related quality of life outcomes with a historical critical illness survivor cohort and overall and mental health-related quality of life with the Dutch population. We included 118 patients with a median age of 61 years (95% range, 36-77 yr) of whom 79 (68%) were male. At 6 weeks, 13 patients (23%) reported psychologic distress, copresence of probable psychiatric disorders was common, and no decline in psychologic distress was observed throughout follow-up. Coronavirus disease 2019 patients tend to suffer less from posttraumatic stress disorder and reported less severe symptoms of anxiety (Hospital Anxiety and Depression Scale Anxiety Score: 3 [0-17] vs 5 [0-16]; estimated mean difference 2.3 [95% CI, 0.0-4.7];

conclusionsPsychologic distress was common in coronavirus disease 2019 ICU survivors and remained similar until 6 months after hospital discharge. Health-related quality of life increased over time and was higher than in a historical cohort, but was lower than in the Dutch population. Our findings highlight that coronavirus disease 2019 ICU survivors should be monitored after ICU treatment to detect possible psychologic distress.

Indexed as

coronavirus disease 2019depressionintensive care unitpostintensive care syndromeposttraumatic stress disordersevere acute respiratory syndrome coronavirus 2

Identifiers

PMID34396141
PMCPMC8357249
OpenAlexW3193401485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.