Evidence map›Paper›PMID 34396110›Full record

ArticleBrain communications2021

Microarray profiling emphasizes transcriptomic differences between hippocampal

Declan King, Paul A Skehel, Owen Dando, Katie Emelianova, Rona Barron, Thomas M Wishart

Abstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Declan KingCentre for Discovery Brain Sciences, UK Dementia Research Institute, The University of Edinburgh, Edinburgh EH8 9JZ, UK.ORCID https://orcid.org/0000-0002-2434-9317
Paul A SkehelCentre for Discovery Brain Sciences, UK Dementia Research Institute, The University of Edinburgh, Edinburgh EH8 9XD, UK.
Owen DandoCentre for Discovery Brain Sciences, UK Dementia Research Institute, The University of Edinburgh, Edinburgh EH8 9XD, UK.
Katie EmelianovaCentre for Discovery Brain Sciences, UK Dementia Research Institute, The University of Edinburgh, Edinburgh EH8 9XD, UK.
Rona BarronSchool of Health Sciences, Queen Margaret University, Edinburgh EH21 6UU, UK.
Thomas M WishartCollege of Medicine and Veterinary Medicine, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.

Funding

Biotechnology and Biological Sciences Research Council BBS/E/D/20251969
6 · The paper itself

Abstract

Primary hippocampal cell cultures are routinely used as an experimentally accessible model platform for the hippocampus and brain tissue in general. Containing multiple cell types including neurons, astrocytes and microglia in a state that can be readily analysed optically, biochemically and electrophysiologically, such cultures have been used in many

Indexed as

hippocampal culturesmicroarrayneuronaltranscriptome

Identifiers

PMID34396110
PMCPMC8361418

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.