Evidence map›Paper›PMID 34396026›Full record

ArticleAPL bioengineering2021

Topological defects in the mesothelium suppress ovarian cancer cell clearance.

Jun Zhang, Ning Yang, Pamela K Kreeger, Jacob Notbohm

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in APL bioengineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  5. Intercellular friction and motility drive orientational order in cell monolayers.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jun ZhangORCID https://orcid.org/0000-0003-4543-5174
Ning YangDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Pamela K KreegerORCID https://orcid.org/0000-0001-8193-1007
Jacob NotbohmORCID https://orcid.org/0000-0002-9836-4982
University of Wisconsin–Madison · US

Funding

The role of multi-cellular aggregates vs. individual tumor cells in metastasis of high-grade serous ovarian cancerR01CA240965 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KREEGER, PAMELA K · 2020 to 2025
$2.7M
Engineered ECM platforms to analyze progression in high grade serous ovarian cancerR01CA232517 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CAMPAGNOLA, PAUL J, KREEGER, PAMELA K · 2018 to 2022
$2.4M
Soluble and mechanical factors directing mesothelial cell migration in clearance during ovarian cancer metastasisR21CA227922 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI KREEGER, PAMELA K, NOTBOHM, JACOB K · 2019 to 2020
$359k
NCI NIH HHS R01 CA232517NCI NIH HHS R01 CA240965NCI NIH HHS R21 CA227922
6 · The paper itself

Abstract

We investigated an

Identifiers

PMID34396026
PMCPMC8337086
OpenAlexW3193237469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.