Evidence map›Paper›PMID 34395796›Full record

ArticleBio-protocol2018

Using Stable Isotopes in Bone Marrow Derived Macrophage to Analyze Metabolism.

Chih-Wei Ko, Daniel Counihan, David DeSantis, Zach Sedor-Schiffhauer, Michelle Puchowicz, Colleen M Croniger

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chih-Wei KoDepartment of Nutrition, Case Western Reserve University, Cleveland, Ohio, USA.
Daniel CounihanDepartment of Nutrition, Case Western Reserve University, Cleveland, Ohio, USA.
David DeSantisDepartment of Nutrition, Case Western Reserve University, Cleveland, Ohio, USA.
Zach Sedor-SchiffhauerDepartment of Nutrition, Case Western Reserve University, Cleveland, Ohio, USA.
Michelle PuchowiczDepartment of Pediatrics, The University of Tennessee Health Science Center, Memphis TN, USA.
Colleen M CronigerDepartment of Nutrition, Case Western Reserve University, Cleveland, Ohio, USA.
Case Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using gas chromatography mass spectrometry (GC-MS) to analyze the citric acid cycle (CAC) and related intermediates (such as glutamate, glutamine, GABA, and aspartate) is an analytical approach to identify unexpected correlations between apparently related and unrelated pathways of energy metabolism. Intermediates can be as expressed as their absolute concentrations or relative ratios by using known amounts of added reference standards to the sample. GC-MS can also distinguish between heavy labeled molecules (

Indexed as

Bone marrow-derived macrophagesChromatography mass spectrometry methodsGC-MSImmunologyMacrophageMacrophage polarizationMetabolismStable isotopes

Identifiers

PMID34395796
PMCPMC8328603
OpenAlexW2889913256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.