Evidence map›Paper›PMID 34395636›Full record

ArticleJournal of immunology research2021

HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4

Shiguang Yu, Morgan Tripod, Ulus Atasoy, Jing Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shiguang YuDepartment of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID https://orcid.org/0000-0002-7923-3047
Morgan TripodArkansas Bioscience Institute and Department of Biological Science, Arkansas State University, Jonesboro, AR 72467, USA.
Ulus AtasoyDivision of Allergy and Immunology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Jing ChenDepartment of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA.ORCID https://orcid.org/0000-0002-5149-2688
Arkansas State University · USUniversity of Michigan · US

Funding

HuR regulates Th17 cells for promoting autoimmune neuroinflammationR01AI119135 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI YU, SHIGUANG · 2015 to 2019
$1.8M
NIAID NIH HHS R01 AI119135
6 · The paper itself

Abstract

After antigen and/or different cytokine stimulation, CD4

Indexed as

Signal TransductionAnimalsCD4-Positive T-LymphocytesCell DifferentiationCytokinesELAV-Like Protein 1ImmunophenotypingInterleukin-6Lymphocyte ActivationMaleMiceMice, KnockoutMice, TransgenicPolyribosomesReceptors, Interleukin-6STAT3 Transcription FactorCytokinesElavl1 protein, mouseELAV-Like Protein 1Il6ra protein, mouseInterleukin-6interleukin-6, mouseReceptors, Interleukin-6STAT3 Transcription Factor

Identifiers

PMID34395636
PMCPMC8357502
OpenAlexW3187552556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.