ArticleFrontiers in ecology and evolution2018
Negative Frequency-Dependent Selection Is Frequently Confounding.
Article in Frontiers in ecology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Article
- Genetic diversification ofApplied and environmental microbiology · 2026Article
- Limits to the evolution of metabolic dependency in spatially structured microbial communities.iScience · 2026Article
- Epistasis mediates the role of negative frequency-dependent selection in bacterial strain structure.PLoS computational biology · 2026Article
- Twenty years of tuberculosis-driven selection shaped the evolution of the meerkat major histocompatibility complex.Nature ecology & evolution · 2025Article
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Student-led experimental evolution reveals novel biofilm regulators of adaptation to multiple niches.bioRxiv : the preprint server for biology · 2025Article
- Sexual selection and predator response in a male-polymorphic livebearing fish.Ethology : formerly Zeitschrift fur Tierpsychologie · 2025Article
- Within-host competition causes pathogen molecular evolution and perpetual microbiota dysbiosis.The ISME journal · 2025Article
- The evolution of antibiotic resistance in Europe, 1998-2019.PLoS pathogens · 2025Article
- Microbial diversification is maintained in an experimentally evolved synthetic community.mSystems · 2024Article
- When does antimicrobial resistance increase bacterial fitness? Effects of dosing, social interactions, and frequency dependence on the benefits of AmpCEvolution letters · 2024Article
- More evidence for widespread antagonistic pleiotropy in polymorphic disease alleles.Frontiers in genetics · 2024Review
- Bird clades with less complex appendicular skeletons tend to have higher species richness.Nature communications · 2023Article
- Evaluating the evolutionary mechanisms maintaining alternative mating strategies in a simulated bull trout (Ecology and evolution · 2023Article
- The role of bacteriophages in shaping bacterial composition and diversity in the human gut.Frontiers in microbiology · 2023Review
- Measuring frequency-dependent selection in culture.Nature human behaviour · 2022Article
- Article
- Population biology of accessory gland-expressed de novo genes in Drosophila melanogaster.Genetics · 2022Article
- Article
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Abstract
Persistent genetic variation within populations presents an evolutionary problem, as natural selection and genetic drift tend to erode genetic diversity. Models of balancing selection were developed to account for the maintenance of genetic variation observed in natural populations. Negative frequency-dependent selection is a powerful type of balancing selection that maintains many natural polymorphisms, but it is also commonly misinterpreted. This review aims to clarify the processes underlying negative frequency-dependent selection, describe classes of polymorphisms that can and cannot result from these processes, and discuss the empirical data needed to accurately identify processes that generate or maintain diversity in nature. Finally, the importance of accurately describing the processes affecting genetic diversity within populations as it relates to research progress is considered.
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