Evidence map›Paper›PMID 34395423›Full record

ArticleFrontiers in cell and developmental biology2021

Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing.

Haiying Sun, Tian Wang, Patrick J Atkinson, Sara E Billings, Wuxing Dong, Alan G Cheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Haiying SunDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Tian WangDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Patrick J AtkinsonDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Sara E BillingsDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Wuxing DongDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Alan G ChengDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Stanford University · USHuazhong University of Science and Technology · CN

Funding

Mouse vestibular regeneration and functionR01DC016919 · NIDCD · STANFORD UNIVERSITY · PI Alan Gi-Lun Cheng · 2019 to 2026
$4.9M
Designing new aminoglycosides to alleviate inner ear toxicityR01DC014720 · NIDCD · STANFORD UNIVERSITY · PI CHENG, ALAN GI-LUN, RICCI, ANTHONY J · 2016 to 2020
$3.0M
COCHLEAR MECHANICSR01DC001910 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI RHODE, WILLIAM S. · 1993 to 2007
$1.4M
NIDCD NIH HHS R01 DC001910NIDCD NIH HHS R01 DC014720NIDCD NIH HHS R01 DC016919
6 · The paper itself

Abstract

The G protein-coupled receptor (GPR) family critically regulates development and homeostasis of multiple organs. As a member of the GPR adhesion family, Gpr125 (Adgra3) modulates Wnt/PCP signaling and convergent extension in developing zebrafish, but whether it is essential for cochlear development in mammals is unknown. Here, we examined the

Indexed as

cochleaGpr125hair celllesser epithelial ridgespiral ganglion neurons

Identifiers

PMID34395423
PMCPMC8355630
OpenAlexW3186980566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.