Evidence map›Paper›PMID 34395406›Full record

ArticleFrontiers in bioengineering and biotechnology2021

A Novel Bionic Catalyst-Mediated Drug Delivery System for Enhanced Sonodynamic Therapy.

Yiling Yang, Shaohua Hua, Weilong Suo, Wenbin Wang, Longhao Wang, Zhengguang Chen, Kefeng Liu, Jie Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yiling YangDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shaohua HuaDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Weilong SuoKey Laboratory of Applied Chemistry and Nanotechnology at Universities of Jilin Province, Changchun University of Science and Technology, Changchun, China.
Wenbin WangAcademy of Medical Sciences, Zhengzhou University, Zhengzhou, China.
Longhao WangAcademy of Medical Sciences, Zhengzhou University, Zhengzhou, China.
Zhengguang ChenDepartment of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kefeng LiuDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jie ZhaoDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CNZhengzhou University · CNChangchun University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound (US)-triggered sonodynamic therapy (SDT) proves itself to be a formidable tool in the fight against cancer, due to its large spectrum of uses as a non-invasive therapeutic measure, while also demonstrating itself to be a certain improvement upon traditional SDT therapeutics. However, tumor hypoxia remains to be a major challenge for oxygen-dependent SDT. This study describes the development of an innovative, multi-use, catalyst-based and improved SDT targeting cancer, through the employment of a sonosensitizing curcumin (Cur) load embedded within a MnO

Indexed as

catalystcurcuminhollowed MnO2sonodynamic therapytumor cell membrane

Identifiers

PMID34395406
PMCPMC8361452
OpenAlexW3188544069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.