ArticleFrontiers in pediatrics2021
A Novel Framework for Phenotyping Children With Suspected or Confirmed Infection for Future Biomarker Studies.
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Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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26citing papers in PubMed, 1 pooled it
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transcript host-RNA signatures to discriminate bacterial and viral infections in febrile children.Pediatric research · 2022Pooled it
- Predicting trajectories of illness using RNA velocity of whole blood.Nature communications · 2026Observational
- Diagnostic multiparametric models and antibiotic practices in febrile infants younger than 90 days.European journal of pediatrics · 2025Observational
- Point-of-care lung ultrasound to differentiate bacterial and viral lower respiratory tract infections in pediatric age: a multicenter prospective observational study.Scientific reports · 2025Observational
- Immunity to Streptococcus pyogenes and Common Respiratory Viruses at Age 0 to 4 Years After COVID-19 Restrictions.JAMA network open · 2025Article
- An international standardization to study the clinical use of lung ultrasound to discriminate viral, bacterial and atypical pneumonia in children with community acquired pneumonia.Italian journal of pediatrics · 2025Article
- Development of a Reference Standard to Assign Bacterial Versus Viral Infection Etiology Using an All-inclusive Methodology for Comparison of Novel Diagnostic Tool Performance.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- The biosensor using the target urine volatile organic compounds for detecting diabetic kidney disease.Scientific reports · 2025Article
- The value of white blood cell count in predicting serious bacterial infections in children presenting to the emergency department: a multicentre observational study.Archives of disease in childhood · 2025Observational
- Article
- Impact of COVID-19 non-pharmaceutical interventions on bacterial infections in children: an international electronic health record-based study.BMJ public health · 2025Article
- Shared neutrophil and T cell dysfunction is accompanied by a distinct interferon signature during severe febrile illnesses in children.Nature communications · 2024Article
- Integration and validation of host transcript signatures, including a novel 3-transcript tuberculosis signature, to enable one-step multiclass diagnosis of childhood febrile disease.Journal of translational medicine · 2024Article
- Where to start? The Irish Emergency Department Antimicrobial Discharge (EDAD) study: a multicentre, prospective cohort analysis.JAC-antimicrobial resistance · 2024Article
- Raising AWaRe-ness of Antimicrobial Stewardship Challenges in Pediatric Emergency Care: Results from the PERFORM Study Assessing Consistency and Appropriateness of Antibiotic Prescribing Across Europe.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Antimicrobial Stewardship in Pediatric Emergency Medicine: A Narrative Exploration of Antibiotic Overprescribing, Stewardship Interventions, and Performance Metrics.Children (Basel, Switzerland) · 2024Review
- Utility of Rapid Nasopharyngeal Swab for Respiratory Pathogens in the Diagnosis of Viral Infections in Children Hospitalized with Fever: A Prospective Validation Study to Improve Antibiotic Use.Children (Basel, Switzerland) · 2024Article
- Rapid molecular diagnostic tests fail to PERFORM in febrile children.The Lancet regional health. Europe · 2023Article
- Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature.Journal of the Pediatric Infectious Diseases Society · 2023Article
- Precision diagnostics in children.Cambridge prisms. Precision medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
34 authors.
Ruud G NijmanSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Rianne OostenbrinkDepartment of General Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
Henriette A MollDepartment of General Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands.
Climent Casals-PascualNuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Ulrich von BothDivision of Pediatric Infectious Diseases, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-University, Munich, Germany.
Aubrey CunningtonSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Tisham DeSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Irini EleftheriouSecond Department of Pediatrics, P. and A. Kyriakou Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Marieke EmontsPediatric Immunology, Infectious Diseases and Allergy Department, Great North Children's Hospital, Newcastle upon Tyne Hospitals Foundation Trust, Newcastle upon Tyne, United Kingdom.
Colin FinkMicropathology Ltd., Warwick, United Kingdom.
Michiel van der FlierSection Pediatric Infectious Diseases, Laboratory of Medical Immunology, Pediatric Infectious Diseases and Immunology, Radboud Centre for Infectious Diseases, Amalia Children's Hospital, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.
Ronald de GrootSection Pediatric Infectious Diseases, Laboratory of Medical Immunology, Pediatric Infectious Diseases and Immunology, Radboud Centre for Infectious Diseases, Amalia Children's Hospital, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, Netherlands.
Myrsini KaforouSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Benno KohlmaierDepartment of General Pediatrics, Medical University of Graz, Graz, Austria.
Taco W KuijpersDepartment of Pediatric Immunology, Rheumatology and Infectious Diseases, Amsterdam University Medical Center, Location Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.
Emma LimPediatric Immunology, Infectious Diseases and Allergy Department, Great North Children's Hospital, Newcastle upon Tyne Hospitals Foundation Trust, Newcastle upon Tyne, United Kingdom.
Ian K MaconochieDepartment of Pediatric Accident and Emergency, Imperial College NHS Healthcare Trust, London, United Kingdom.
Stephane PaulusDepartment of Pediatrics, Children's Hospital, John Radcliffe, University of Oxford, Level 2, Oxford, United Kingdom.
Federico Martinon-TorresGenetics, Vaccines, Infections and Pediatrics Research Group, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Marko PokornDepartment of Infectious Diseases, University Medical Centre Ljubljana, Univerzitetni Klinični Centre, Ljubljana, Slovenia.
Sam T RomaineInstitute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
Irene Rivero CalleGenetics, Vaccines, Infections and Pediatrics Research Group, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Luregn J SchlapbachDepartment of Intensive Care and Neonatology, Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Frank J SmitDepartment of Pediatrics, Maasstad Hospital, Rotterdam, Netherlands.
Maria TsoliaGerman Centre for Infection Research, DZIF, Partner Site Munich, Munich, Germany.
Effua UsufChild Survival, Medical Research Council: The Gambia Unit, Fajara, Gambia.
Victoria J WrightSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Shunmay YeungFaculty of Tropical and Infectious Disease, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Dace ZavadskaDepartment of Pediatrics, Children Clinical University Hospital, Rigas Stradina Universitāte, Riga, Latvia.
Werner ZenzDepartment of General Pediatrics, Medical University of Graz, Graz, Austria.
Michael LevinSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Jethro A HerbergSection of Pediatric Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College of Science, Technology and Medicine, London, United Kingdom.
Enitan D CarrolInstitute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
PERFORM consortium (Personalized Risk assessment in febrile children to optimize Real-life Management across the European Union)
Funding
Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
biomarkerschildrenclinical phenotypessepsisserious bacterial infection
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