Evidence map›Paper›PMID 34395321›Full record

ArticleIranian journal of otorhinolaryngology2021

Necessity of Fine-Needle Aspiration in Probably Benign Sonographic Appearance of Thyroid Nodules.

Aida Sharifi Haddad, Behzad Aminzadeh, Seyed Ali Alamdaran, Shokoufeh Bonakdaran, Amirhosein Jafarian, Samira Rahemi, Negar Morovatdar, Ramesh Giti

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of otorhinolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aida Sharifi HaddadDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Behzad AminzadehDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed Ali AlamdaranSurgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Shokoufeh BonakdaranDepartment of Internal, Faculty of Medicine Mashhad University of Medical Sciences, Mashhad, Iran.
Amirhosein JafarianDepartment of Pathology, Faculty of Medicine Mashhad University of Medical Sciences, Mashhad, Iran.
Samira RahemiDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Negar MorovatdarClinical Research Units, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ramesh GitiDepartment of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe management of thyroid nodules has been proposed based on US features and information obtained from Fine-Needle Aspiration Cytology (FNAC). In this study, we checked the diagnostic value of ultrasound in comparison with FNAC in probably benign nodules of thyroid. MATERIALS AND

methodsPatients with thyroid nodules referred to the Radiology department from 2015 to 2020, were classified into five types based on the American College of Radiology/thyroid imaging reporting and data system (TI-RADS) standards. The patients with TI-RADS III-V were examined by FNA biopsy. Subsequently, the collected data of 535 patients having thyroid nodules with TI-RADS III were statistically analyzed.

resultsThe mean age of the patients was estimated at 46.57. The analysis of TI-RADS III cases examined by the FNA biopsy revealed that 99.1% of the cases were diagnosed with benign lesions. The mean size of benign and malignant nodules was 27mm and 41mm, respectively. There was no significant correlation between the size of the nodules or patients age, and thyroid malignancy (P-values > 0.05).

conclusionThere was a very low chance of malignancy (0.9%) in thyroid nodules with thyroid imaging classification of TI-RADS III. Furthermore, no meaningful correlation was observed between the size of the nodules and their malignancy. Therefore, the use of FNAC, based on the current guidelines, on thyroids for nodules larger than 2.5 cm might need to be revised.

Indexed as

FNAMalignancyThyroid noduleTI-RADS

Identifiers

PMID34395321
PMCPMC8339888
OpenAlexW3174408493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.