ArticleEuropean thyroid journal2021
2021 European Thyroid Association Guidelines for the Management of Iodine-Based Contrast Media-Induced Thyroid Dysfunction.
Article in European thyroid journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- The effect of iodinated contrast media on thyroid (dys)function in children.European thyroid journal · 2026Pooled it
- Perchlorates in the treatment of hyperthyroidism and thyrotoxicosis: a comprehensive review.Endocrine · 2024Pooled it
- Assessing the impact of short-term Lugol's solution on toxic nodular thyroid disease: a pre-post-intervention study.Frontiers in endocrinology · 2024Trial
- Iodinated Contrast Media in Oncologic CT: A Narrative Review of Safety, Risk Stratification, and Practical Considerations.Diagnostics (Basel, Switzerland) · 2026Review
- Approach to the patient with thyroid storm.The Journal of clinical endocrinology and metabolism · 2026Review
- Article
- Hypothyroidism in Infants after Enteral Administration of Iodinated Contrast Media: A Rare but Serious Complication.Hormone research in paediatrics · 2026Observational
- Short-term effect of iodine contrast medium on thyroid function: a prospective cohort study.Annals of medicine · 2025Article
- [Abnormal thyroid markers in critically ill patients-harmless irritation or a real problem?]Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Review
- Article
- National recommendations of the Croatian society of medical biochemistry and laboratory medicine: Thyroid function tests from the laboratory point of view.Biochemia medica · 2025Review
- Iodinated contrast media (ICM)-induced thyroid dysfunction: a review of potential mechanisms and clinical management.Clinical and experimental medicine · 2025Review
- Utility of ultra-portable ultrasound devices for the risk-stratification of thyroid dysfunctions in an emergency setting.Journal of endocrinological investigation · 2025Article
- Critical reflection on the indication for computed tomography: an interdisciplinary survey of risk and benefit management in patients with sepsis.Insights into imaging · 2025Article
- Case Report: Acute inferior myocardial infarction and third-degree atrioventricular block in a patient with hyperthyroidism.Frontiers in cardiovascular medicine · 2025Article
- Effects of iodine contrast media on thyroid function - a prospective study.European thyroid journal · 2024Article
- The Impact of Iodinated Contrast Media Used in Epidural Steroid Injections on Thyroid Function Tests.Cureus · 2024Article
- The ETA-ESE statement on the European Chemicals Agency opinion on iodine as an endocrine disruptor.European thyroid journal · 2024Article
- Iodine contrast should be avoided in patients with thyroid eye disease.Frontiers in ophthalmology · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Given the fact that a large number of radiological examinations using iodine-based contrast media (ICM) are performed in everyday practice, clinicians should be aware of potential ICM-induced thyroid dysfunction (TD). ICM can induce hyperthyroidism (Hyper) or hypothyroidism (Hypo) due to supraphysiological concentrations of iodine in the contrast solution. The prevalence of ICM-induced TD varies from 1 to 15%. ICM-induced Hyper is predominantly found in regions with iodine deficiency and in patients with underlying nodular goiter or latent Graves' disease. Patients at risk for ICM-induced Hypo include those with autoimmune thyroiditis, living in areas with sufficient iodine supply. Most cases of ICM-induced TD are mild and transient. In the absence of prospective clinical trials on the management of ICM-induced TD, an individualized approach to prevention and treatment, based on patient's age, clinical symptoms, pre-existing thyroid diseases, coexisting morbidities and iodine intake must be advised. Treatment of ICM-induced Hyper with antithyroid drugs (in selected cases in combination with sodium perchlorate) should be considered in patients with severe or prolonged hyperthyroid symptoms or in older patients with underlying heart disease. It is debated whether preventive therapy with methimazole and/or perchlorate prior to ICM administration is justified. In ICM-induced overt Hypo, temporary levothyroxine may be considered in younger patients with symptoms of Hypo, with an underlying autoimmune thyroiditis and in women planning pregnancy. Additional clinical trials with clinically relevant endpoints are warranted to further aid in clinical decision-making in patients with ICM-induced TD.
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